Results 161 to 170 of about 185,548 (298)

Controlling pre-leukemic thymocyte self-renewal [PDF]

, 2014
Goossens, Steven, Van Vlierberghe, Pieter   +1 more
core   +2 more sources

Chemotherapy‐driven expression of WNT ligands in bone marrow stromal cells contributes to chemoresistance in acute lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Chemotherapy‐induced WNT ligand secretion by bone marrow (BM) stroma drives acute lymphoblastic leukaemia (ALL) chemoresistance. WNT pathway inhibition disrupts this cross‐talk and restores therapeutic response, highlighting WNT inhibitors as a promising strategy to prevent relapse in ALL.
Foteini Kalampalika, Amanda Jiménez‐Pompa, Raúl Sánchez‐Lanzas, Bela Patel, Miguel Ganuza   +4 more
wiley   +1 more source

Ferroptosis: a new dawn in the treatment of acute lymphoblastic leukemia. [PDF]

Front Oncol
Han J, Yang Y, Wei Y, Jin J, Feng W.
europepmc   +1 more source

CCR4 expression defines a targetable subset of T-cell acute lymphoblastic leukemia. [PDF]

Blood Adv
Xu J, McCoy M, Martinez Z, Sussman JH, Gao D, Vincent T, Wang H, Ma C, Elghawy O, Chen GM, Yang AG, Pölönen P, Natan K, Shraim R, Newman H, Hofmann TJ, Scoma S, DiNofia AM, Hunger SP, Yang JJ, Mullighan CG, Bernt KM, Hexner EO, Grupp SA, Watanabe K, June CH, Tan K, Teachey DT, Diorio C.   +28 more
europepmc   +1 more source

Altered cytoskeletal integrity underlies impaired platelet shape change and defective thrombus formation in ETV6‐related thrombocytopenia

British Journal of Haematology, EarlyView.
Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov, Julia‐Jessica D. Korobkin, Daria V. Fedorova, Sofia V. Galkina, Maria M. Golomysova, Sergei I. Obydennyi, Anastasia A. Ignatova, Ekaterina‐Iva A. Adamanskaya, Eugenia V. Yushkova, Anna V. Pavlova, Pavel A. Zharkov, Igor I. Kireev, Galina A. Novichkova, Viktor G. Zgoda, Mikhail A. Panteleev, Anastasia N. Sveshnikova   +15 more
wiley   +1 more source

A Unique Case of Concomitant T-Prolymphocytic Leukemia and B-Cell Acute Lymphoblastic Leukemia. [PDF]

EJHaem
Patel VM, Hyak J, Laknezhad S, Chintapenta M, Patel P, Chen W, Kainthla R.   +6 more
europepmc   +1 more source

ELDA: real-time functional drug profiling in acute lymphoblastic leukemia. [PDF]

Front Oncol
Mariano SS, Assis LHP, Correa JR, Canevarolo RR, Migita NA, Sudalagunta PR, de Azevedo AC, Meidanis J, Brandalise SR, Silva AS, Yunes JA.   +10 more
europepmc   +1 more source

Impact of CD34+ cell dose on outcomes of related allogeneic PBSCT in adult AML patients

British Journal of Haematology, EarlyView.
Summary CD34+ cell dose is believed to impact the outcomes of allogeneic peripheral blood stem cell transplantation (PBSCT), yet the optimal dose remains unclear. We retrospectively reviewed 2407 adult patients with acute myeloid leukaemia who underwent their first related PBSCT between 2000 and 2019.
Yusuke Toda, Tomoyasu Jo, Yasuyuki Arai, Kaito Harada, Masamitsu Yanada, Takahiro Fukuda, Satoshi Yoshihara, Noriko Doki, Naoyuki Uchida, Yasuo Mori, Yuta Hasegawa, Yukio Kondo, Toshiro Kawakita, Tetsuya Eto, Tetsuya Nishida, Masatsugu Tanaka, Makoto Onizuka, Katsuhiro Shono, Masayuki Hino, Tatsuo Ichinohe, Yoshiko Atsuta, Takaaki Konuma   +21 more
wiley   +1 more source

An integrative molecular map of pediatric B-cell precursor acute lymphoblastic leukemia. [PDF]

Commun Med (Lond)
Krali O, Enblad AP, Sulyaeva J, Gogishvili D, Lundmark A, Harila A, Andersson C, Erkers T, Heinäniemi M, Lönnerholm G, Nordlund J.   +10 more
europepmc   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source