Results 251 to 260 of about 218,068 (352)

Localization of preferential sites of rearrangement within the BCR gene in Philadelphia chromosome-positive acute lymphoblastic leukemia.

, 1989
Christopher T. Denny, Neil P. Shah, S Ogden, Cheryl L. Willman, T.S. McConnell, W M Crist, AJ Carroll, Owen N. Witte   +7 more
openalex   +1 more source

CRISPR‐Cas9 screen reveals that inhibition of enhancer of zeste homolog 2 sensitizes malignant T cells to dimethyl‐fumarate‐induced cell death

The FEBS Journal, EarlyView.
A genome‐wide CRISPR‐Cas9 screen identified H3K27 methylation as a key regulator of T‐cell lymphoma sensitivity to dimethyl fumarate (DMF). Specifically, inhibition of enhancer of zeste homolog 2 (EZH2) enhanced DMF‐induced cell death in malignant T cells. These results provide functional evidence for the role of EZH2 in modulating drug sensitivity and
Jan P. Teubner, Deniz Tümen, Arne Kandulski, Philipp Heumann, Patricia Mester, Elisabeth Aschenbrenner, Kirstin Pollinger, Manuela Gunckel, Barbara Volz, Tobias Hein, Paul L. Beltzig, Luisa Tengler, Florian Voll, Marina Kreutz, Claudia Kunst, Jan P. Nicolay, Martina Müller, Karsten Gülow   +17 more
wiley   +1 more source

Retrospective analysis of asparaginase-associated pancreatitis in pediatric acute lymphoblastic leukemia: focus on rechallenge with pegaspargase. [PDF]

J Cancer Res Clin Oncol
Jia C, Li Q, Zhai X, Quan M, Bai B, Ding X.   +5 more
europepmc   +1 more source

The Association of IL‐17RC Polymorphisms rs708567 and rs76999397 With Acute Lymphoblastic Leukaemia

International Journal of Immunogenetics, EarlyView.
ABSTRACT Background: Acute lymphoblastic leukaemia (ALL) is characterized by the clonal proliferation of immature lymphoid precursors in the bone marrow or peripheral blood. This study investigates whether genetic polymorphisms in IL‐17RC are associated with an increased risk of ALL in the Saudi population.
Ali Aljuaimlani, Lamjed Mansour, Jameel Al‐Tamimi, Jamilah Alshammari, Safa A. Alqarzae, Fadwa M. Alkhulaifi, Suliman Alomar   +6 more
wiley   +1 more source

A Decade of Transformation in the Management of Childhood Acute Lymphoblastic Leukemia: From Conventional Chemotherapy to Precision Medicine. [PDF]

Pediatr Rep
Aricò M, Conter V.
europepmc   +1 more source

18F-FDG PET/CT radiomic analysis with machine learning for identifying bone marrow involvement in the patients with suspected relapsed acute leukemia [PDF]

, 2019
Hao, Keji, Li, Hebei, Wahl, Richard L., Wang, Qian, Wang, Xiuying, Xin, Bowen, Xu, Chongrui, Zhao, Yunyun, Zheng, Chaojie, Zhou, Yun   +9 more
core   +1 more source

The PNH French Working Group Experience: Building a Strong Network of Cytometrists

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Orianne Wagner‐Ballon, Magali Le Garff‐Tavernier, Rémi Lestestu, Bernard Drenou, Agathe Debliquis, the PNH French Working Group «CytHem‐HPN», Chantal Fossat, Claire Loosen, Bernard Chatelain, Marie Loosveld   +9 more
wiley   +1 more source

The Application of Artificial Intelligence‐Based Bone Marrow Cell Analysis System in Pediatric Hematological Diseases

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The clinical diagnosis of hematological diseases depends on the differential count of nucleated cells on the bone marrow (BM) smears, and an artificial intelligence (AI)‐based system was applied to automatically classify BM nucleated cells in pediatric hematological disease samples in this study.
Xin He, Fei He, Yan Wang, Yu Liu, Xiaopeng Gao, Mingrui Yu, Haiyan Gao   +6 more
wiley   +1 more source

Correction to "Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients". [PDF]

Hemasphere
europepmc   +1 more source

Acute lymphoblastic B‐cell leukemia or CAR‐T cell related skin changes – a relevant diagnostic challenge

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Farzan Solimani, Amrei Dilling, Konrad Heisterkamp, Frederik Damm, Olaf Penack, Christian Oberender, Philipp Le‐Coutre, Martina Rudelius, Kamran Ghoreschi, Alexander Nast   +9 more
wiley   +1 more source