Results 261 to 270 of about 223,598 (343)
V-H gene usage differs in germline and mutated B-cell chronic lymphocytic leukemia [PDF]
Amlot, P +8 more
core
DNTTIP1 drives leukaemogenesis through MiDAC‐mediated epigenetic silencing of BMF
DNTTIP1 cooperates with SP1 to recruit HDAC1/2, leading to BMF silencing and reduced competitive binding of BMF to BCL2.This suppresses autophagy and apoptosis, promoting leukaemic cell survival. Targeting the DNTTIP1‐HDAC1/2‐BMF axis reactivates BMF and induces anti‐leukaemic effects.
Ruolin Xiu +12 more
wiley +1 more source
Advances in Acute Lymphoblastic Leukemia Review Series.
Senapati J, Short NJ.
europepmc +1 more source
Molecular genetic characteristics and clinical significance of childhood acute lymphoblastic leukemia. [PDF]
Zhu Z, Yan J.
europepmc +1 more source
A Human Model of Oligodendrocyte Development Shows MCL‐1 Influences Oligodendrocyte Morphogenesis
A unified model of oligodendrocyte differentiation from human embryonic stem cells revealed that MCL‐1 is critical for regulating the expression of oligodendrocyte‐related genes and the morphogenesis of myelinating oligodendrocytes. ABSTRACT Oligodendrocytes are the myelinating cells of the central nervous system.
Melanie Gil +2 more
wiley +1 more source
MicroRNA-181a in acute lymphoblastic leukemia: expression pattern, target genes and its potential as a biomarker. [PDF]
Jahanpanah M +8 more
europepmc +1 more source
[Acute lymphoblastic leukemia].
P, Stavem, P F, Hjort
openaire +1 more source
ABSTRACT Background Patients with haematological cancer often exhibit reduced cardiorespiratory fitness and an elevated risk of cardiovascular disease. The mechanisms underlying this impairment are multifactorial, but the contribution of skeletal muscle fat infiltration has not been evaluated.
Nicholas J. Saner +7 more
wiley +1 more source
Insights into the Prognostic Value of Telomere Length in Childhood Acute Lymphoblastic Leukemia. [PDF]
Vakonaki E +10 more
europepmc +1 more source
Abstract Background Immunophenotypically defined mixed‐phenotype acute leukemias (MPAL) are rare and remain a diagnostic and therapeutic dilemma. We aim to explore the clinicopathologic characteristics and oncological outcomes of these entities. Methods A total of 52 patients with immunophenotypically defined MPAL were identified from our pathology ...
Bo Zhang +5 more
wiley +1 more source

