Results 81 to 90 of about 131,024 (143)

MMIL: A novel algorithm for disease associated cell type discovery [PDF]

arXiv
Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization method that enables the training and calibration of cell-level classifiers using patient-level labels. Our approach can
arxiv  

Clinical Validation of a Real-Time Machine Learning-based System for the Detection of Acute Myeloid Leukemia by Flow Cytometry [PDF]

arXiv
Machine-learning (ML) models in flow cytometry have the potential to reduce error rates, increase reproducibility, and boost the efficiency of clinical labs. While numerous ML models for flow cytometry data have been proposed, few studies have described the clinical deployment of such models.
arxiv  

Reverse Degree-Based Topological Indices and QSPR Analysis of Cancer Drugs [PDF]

arXiv
A topological index of a graph $G$ is a numerical quantity that describes its topology. Reverse degree-based topological indices play an important role in finding topological descriptors. Azacitidine, Decitabine, and Guadecitabine are hypomethylating agents which are used for the treatment of patients with higher-risk myelodysplastic syndromes, acute ...
arxiv  

Acute Myeloid Leukemia Associated Leukocytic Hypophysitis Presenting with Central Diabetes Insipidus

AACE Clinical Case Reports, 2018
: Objective: Central diabetes insipidus is a rare complication of acute myeloid leukemia and myelodysplastic syndrome. To date there are fewer than 100 cases reported in the literature, and no published case reports in the endocrinology literature.
Joshua A. Levine, MD, PhD, Ashley Pariser, MD, Eve Bloomgarden, MD   +2 more
doaj  

Cytarabine-Induced Hyperbilirubinemia in a Pregnant Patient With Acute Myeloid Leukemia. [PDF]

ACG Case Rep J
Rajan A, Ahmed A, Dehghan Y, Hsieh JC, Moore C.   +4 more
europepmc   +1 more source

Diagnostic and Therapeutic Implications of the SUMOylation Pathway in Acute Myeloid Leukemia. [PDF]

Cancers (Basel)
Chatzikalil E, Arvanitakis K, Filippatos F, Diamantopoulos PT, Koufakis T, Solomou EE.   +5 more
europepmc   +1 more source

The Role of the Sirtuin Family Histone Deacetylases in Acute Myeloid Leukemia-A Promising Road Ahead. [PDF]

Cancers (Basel)
Strzałka P, Krawiec K, Wiśnik A, Jarych D, Czemerska M, Zawlik I, Pluta A, Wierzbowska A.   +7 more
europepmc   +1 more source

α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia.

Blood
Millman SE, Chaves-Perez A, Janaki-Raman S, Ho YJ, Morris JP, Narendra V, Chen CC, Jackson BT, Yashinskie JJ, Mezzadra R, Devine TI, Barthet VJA, Saoi M, Baslan T, Tian S, Sachs Z, Finley LWS, Cross JR, Lowe SW.   +18 more
europepmc   +1 more source

The epigenetic role of EZH2 in acute myeloid leukemia. [PDF]

PeerJ
Fang J, Zhang J, Zhu L, Xin X, Hu H.
europepmc   +1 more source

Assessment of chromatin remodeling of acute myeloid leukemia cells treated with gilteritinib: a case report. [PDF]

J Med Case Rep
Mori J, Sawada T, Nojiri K, Kanemoto Y, Okada T, Kurokawa T, Kato S.   +6 more
europepmc   +1 more source