Results 91 to 100 of about 2,838,728 (307)

Bio‐Inspired Pancreas With Microfluidic Multi‐Component Hydrogel Microfibers for Exploring Pancreatic Exocrine and Endocrine Interactions

open access: yesAggregate, EarlyView.
A bionic pancreas model incorporating core‐shell microfibers that encapsulate pancreatic stellate cells (PSCs) and β‐cells provides valuable insights into PSCs activation, cell‐cell interactions, and diabetes progression. Furthermore, the potential of this bio‐inspired pancreas for drug screening is demonstrated by testing with a glucagon‐like peptide ...
Zhikun Huan   +4 more
wiley   +1 more source

Acute pancreatitis associated with the antibiotic levofloxacin: A rare case report

open access: yesClinical Case Reports, 2023
Key Clinical Message Drug‐induced acute pancreatitis is a potentially ignored diagnosis that must be precisely valued. Drug‐induced acute pancreatitis can be considered the third common cause of acute pancreatitis after ruling out alcohol and gallstones.
Pugazhendi Inban   +12 more
doaj   +1 more source

Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities [PDF]

open access: yes, 2017
OBJECTIVES: Chronic pancreatitis (CP) has a profound independent effect on quality of life (QOL). Our aim was to identify factors that impact the QOL in CP patients.
Abberbock, Judah   +23 more
core   +2 more sources

Mortality Patterns and Phenotypic Clusters in Trisomy 13: A Population‐Based Study From Japan

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Trisomy 13, the third most common autosomal trisomy after trisomy 21 and trisomy 18, is associated with a significantly high infant mortality rate. However, large‐scale studies examining causes of death in trisomy 13 remain scarce. Therefore, we aimed to better understand the mortality patterns.
Narumi Kato   +2 more
wiley   +1 more source

GLP‐1 agonist‐associated presentations to unscheduled care: An opportunistic pilot study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The impact of GLP‐1 or GIP/GLP‐1 receptor agonist use on unscheduled care is not well‐described. We conducted a prospective, observational study using opportunistic screening by clinicians as a first step to understanding the effect of GLP‐1 or GIP/GLP‐1 agonists on Emergency Department presentations and to guide future studies.
Oliver Thomas, James Michael Coulson
wiley   +1 more source

Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway

open access: yesOxidative Medicine and Cellular Longevity, 2018
Oxidative stress plays a crucial role in the pathogenesis of acute pancreatitis (AP). Isoliquiritigenin (ISL) is a flavonoid monomer with confirmed antioxidant activity. However, the specific effects of ISL on AP have not been determined.
Xinnong Liu   +11 more
semanticscholar   +1 more source

What's in a Name? Classification of Diabetes Mellitus in Veterinary Medicine and Why It Matters [PDF]

open access: yes, 2016
Diabetes Mellitus (DM) is a syndrome caused by various etiologies. The clinical manifestations of DM are not indicative of the cause of the disease, but might be indicative of the stage and severity of the disease process.
Abdul-Rasoul   +110 more
core   +3 more sources

Machine learning methods for predicting adverse drug events: A systematic review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo   +8 more
wiley   +1 more source

Acute pancreatitis as a risk factor of chronic pancreatitis and pancreatic cancer. An overview

open access: yesBiomedical Papers
This is an overview of relation between acute and chronic pancreatitis and between acute pancreatitis and pancreatic cancer. Acute pancreatitis and recurrent acute pancreatitis are an etiological factor of chronic pancreatitis.
David Solil   +4 more
doaj   +1 more source

Circulating oxylipins predict mortality in heart failure with preserved ejection fraction

open access: yesESC Heart Failure, EarlyView.
A targeted LC–MS lipidomics approach identified arterial 15‐keto PGF2a as associated with 5‐year mortality in 90 patients with HFpEF. Abstract Aims Heart failure with preserved ejection fraction (HFpEF) poses significant diagnostic, prognostic and therapeutic challenges, with high morbidity and mortality rates.
Vaishnavi Aradhyula   +12 more
wiley   +1 more source

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