Results 21 to 30 of about 985,459 (353)

CD14 Is an Acute-Phase Protein [PDF]

open access: yesThe Journal of Immunology, 2004
Abstract The origin of soluble CD14 (sCD14) in the circulation is uncertain. To examine whether CD14 could be an acute-phase protein (APP), the levels of sCD14, IL-6, and C-reactive protein were determined by ELISA in serum and synovial fluid (SF) of patients with various arthropathies, and the regulation of CD14 synthesis was examined ...
Sylvette Bas   +4 more
openaire   +2 more sources

Angiotensinogen: an acute-phase protein? [PDF]

open access: yesHypertension, 1994
Angiotensinogen has been assumed to be an acute-phase protein, because some forms of acute inflammation, eg, the injection of lipopolysaccharide or cellite or partial hepatectomy, increased the hepatic synthesis of angiotensinogen. In addition, the well-characterized nephrectomy-induced stimulation of angiotensinogen was thought to represent an acute ...
M Soden   +3 more
openaire   +3 more sources

Acute-phase protein synthesis: a key feature of innate immune functions of the liver

open access: yesBiological chemistry, 2021
The expression of acute-phase proteins (APP’s) maintains homeostasis and tissue repair, but also represents a central component of the organism’s defense strategy, especially in the context of innate immunity.
C. Ehlting, S. Wolf, J. Bode
semanticscholar   +1 more source

Acute Phase Protein Response in Goats [PDF]

open access: yesJournal of Veterinary Diagnostic Investigation, 2008
Acute phase proteins (APPs) are important diagnostic indicators of inflammatory disturbances in animals. The objectives of the current study were to validate analytical methods for measuring haptoglobin (Hp), serum amyloid A (SAA), acid soluble glycoprotein (ASG), fibrinogen, and albumin concentrations in goats and to evaluate their response to an ...
Laura Soler   +5 more
openaire   +3 more sources

C. elegans feed yolk to their young in a form of primitive lactation

open access: yesNature Communications, 2021
It is unclear why C. elegans continues to produce large quantities of yolk after reproduction. Here the authors show that post-reproductive C. elegans mothers vent yolk which supports their offspring’s growth, serving as a form of primitive lactation.
Carina C. Kern   +8 more
doaj   +1 more source

Acute-phase proteins during inflammatory reaction by bacterial infection: Fish-model

open access: yesScientific Reports, 2019
Acute-phase protein (APPs) serum levels have been studied in many human diseases, and their components contribute to host defense during the evolution of infectious diseases by acting as part of the innate immune system.
I. Charlie-Silva   +13 more
semanticscholar   +1 more source

The importance of acute-phase proteins as markers in cancers

open access: yesStudia Medyczne, 2021
Acute-phase proteins (APPs) form a group of heterogeneous proteins whose synthesis takes place in the liver. This involves mediators such as cytokines and constitutes a response to acute inflammations, bacterial infections, tumours, and autoimmune ...
Paulina Zegarska   +2 more
doaj   +1 more source

Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein

open access: yesKidney International Reports, 2017
Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain (FGA) gene, and it is the most common cause of hereditary renal amyloidosis in the UK.
Dorota Rowczenio   +18 more
doaj   +1 more source

Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel

open access: yesScientific Reports, 2017
Dissociation of the native transthyretin (TTR) tetramer is widely accepted as the critical step in TTR amyloid fibrillogenesis. It is modelled by exposure of the protein to non-physiological low pH in vitro and is inhibited by small molecule compounds ...
Guglielmo Verona   +11 more
doaj   +1 more source

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