Results 71 to 80 of about 7,955,704 (317)

The negative acute phase response of serum transthyretin following Streptococcus suis infection in the pig [PDF]

, 2004
Peer ...
Eckersall, P D, Peter Mikael H. Heegaard,, Waterston, M, Andresen, L O, Eckersall, P.D., Eckersall, PD, Campbell, Fiona, Waterston, Mary, Campbell, F.M., Campbell, Fiona Margaret, Heegaard, PMH, Sorensen, Nanna, P. David Eckersall, Waterston, M., Lars Ole Andresen, Andresen, LO, Peter Mikael H. Heegaard, Campbell, FM, Mary Waterston, Andresen, Lars, Heegaard, P M H, Sørensen, Nanna Skall, David Eckersall, P., Sorensen, NS, Heegaard, Peter M. H., Sorensen, N S, Nanna Skall Sorensen, Andresen, Lars Ole, Fiona M. Campbell, Pallas, E, Complutense Uni, Madrid, Staerk, K D C, SILVA, Joao S., Elton, Debra, Smith, R P, Van Winden, S C L, Newton, J. Richard, Olmeda, S, VRIES, Erik De, Guitian, J, Paillot, Romain, Camacho, A T, Wheelhouse, Nicholas M, HECK, Albert J. R., Hosp Clin Univ, Spain, Grimmett, Humphrey, Entrican, Gary, Watson, E, Paiba, G A, BAKKER, Nicole, Gestal, J J, Lab Lema & Bandin, Spain, Daly, Janet M., Henning, J, Harvard, YATSUDA, Ana Patricia, Pfeiffer, D U, Telford, S, MINEO, Tiago W. P., Ellis-Iversen, J, Hosp Xeral Cies, Spain, SILVA, Neide M., BENEVIDES, Luciana, Hadorn, D C, Snow, L C, KNOX, Dave P., KRIJGSVELD, Jeroen, Mumford, Jennifer A., Goethert, H, Vu, L T, Spielman, A, Cook, A J C   +71 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Rapid and widely disseminated acute phase protein response after experimental bacterial infection of pigs [PDF]

, 2009
Peer ...
Poulsen, K.T., Skovgaard, K., Mortensen, S., Campbell, Fiona M., Eckersall, P.D., Skovgaard, Kerstin, Mortensen, Shila, Shila Mortensen, Boye, M., Eckersall, P. David, Eckersall, P. D., Campbell, F. M., Campbell, F.M., Poulsen, Karin T., Wendt, Karin Tarp, P. David Eckersall, Mette Boye, Karin T. Poulsen, Heegaard, P.M.H., Peter M.H. Heegaard, Kerstin Skovgaard, Boye, Mette, Heegaard, Peter M. H., Fiona M. Campbell, Heegaard, Peter M.H.   +24 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Acute phase biomarkers of diseases in small ruminants: an overview [PDF]

Bulgarian Journal of Veterinary Medicine, 2019
Acute phase proteins (APPs) are a large group of proteins synthesised mainly by the liver. Their production is stimulated in response to disturbances in the systemic homeostasis. It is known that each species has a specific set of APPs.
P. Iliev , T. M. Georgieva
doaj   +1 more source

Proteomic profiling following immunoaffinity capture of HDL: Association of acute phase proteins and complement factors with pro-inflammatory HDL in Rheumatoid Arthritis

Arthritis & Rheumatism, 2012
Objective To utilize proteomic analysis to identify protein biomarkers associated with pro-inflammatory HDL in patients with active rheumatoid arthritis. Methods Liquid chromatography-mass spectrometry (LC-MS) was used to analyze proteins associated with
J. Watanabe, C. Charles-Schoeman, Y. Miao, D. Elashoff, Yuen-Yin Lee, G. Katselis, Terry D. Lee, S. Reddy   +7 more
semanticscholar   +1 more source

Green tea extract supplementation ameliorates CCl4-induced hepatic oxidative stress, fibrosis, and acute-phase protein expression in rat

, 2014
Background/Purpose: We evaluated the long-term effects of green tea extract (GTE) supplementation on oxidative stress, biliary acute phase protein expression, and liver function in CCl4-induced chronic liver injury. Methods: We evaluated the antioxidant
李光倫 ;鄭劍廷 ;李宣書, Hung, Guo-Dung;Li, Ping-Chia;Lee, Hsuan-Shu;Chang, Huei-Min;Chien, Chiang-Ting;Lee, Kuang-Lun   +1 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A comparison of the acute phase proteins in chronic aortic occlusion versus diffuse aortoiliac occlusive disease [PDF]

Hospital Pharmacology, 2014
Background The purpose of the present study is to evaluate if there is a specific relationship of the acute-phase proteins between patients with the chronic aortic occlusion (COA) and patients with diffuse aortoiliac occlusive disease (AIOD), and to ...
Ilić Nikola S., Končar Igor B., Dragaš Marko V., Golubović Milka T., Marković Miroslav D., Sladojević Miloš M., Cvetković Slobodan D., Davidović Lazar B.   +7 more
doaj   +1 more source