Results 131 to 140 of about 264,861 (313)

Acute Promyelocytic Leukemia Complicated by Deep Venous Thrombosis, Pulmonary Thromboembolism, and Hematemesis

Indian Journal of Clinical Cardiology
Acute promyelocytic leukemia (APML) is a myeloid leukemia classified as M3-AML. It is known for its bleeding diathesis, which is predominantly driven by disseminated intravascular coagulation and primary hyperfibrinolysis.
Sudipta Mondal, Saurav Banerjee
doaj   +1 more source

Central Nervous System Double Relapse of Acute Promyelocytic Leukemia and Acute Myelomonocytic Leukemia

Case Reports in Hematology, 2019
Relapse of acute promyelocytic leukemia (APL) and non-M3-acute myeloid leukemia in the central nervous system (CNS) are rare events. Here, we describe a case of simultaneous relapses of APL and acute myelomonocytic leukemia on the CNS of a patient after ...
Laura M. Stanko, Vishnu Reddy, Fady M. Mikhail, Nikolaos Papadantonakis   +3 more
doaj   +1 more source

Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells [PDF]

, 2005
Yoko Tabe, Marina Konopleva, Rooha Contractor, Mark F. Munsell, Wendy Schober, Linhua Jin, Yuko Tsutsumi‐Ishii, Isao Nagaoka, J Igari, Michael Andreeff   +9 more
openalex   +1 more source

Molecular landscape of acute promyelocytic leukemia at diagnosis and relapse

Haematologica, 2017
Acute promyelocytic leukemia (APL) occurs in about 5–30% of adult de novo AML and is characterized by the presence of the chromosomal translocation t(15;17)(q24;q21).
A. Fasan, C. Haferlach, K. Perglerová, W. Kern, T. Haferlach   +4 more
semanticscholar   +1 more source

Acute lower limb ischemia revealing hypo granular acute promyelocytic leukemia

Leukemia Research Reports
Introduction: Acute promyelocytic leukemia (AML-M3), classified as acute Myeloid leukemia with PML RARA according to the 5th edition of the World Health Organization classification of haematolymphoid tumors 2022 [1], is marked by abnormal promyelocyte ...
Sabrina Belmahi, Zainab Kajeiou, Loubna Yacoubi, Noussaiba Azzi, Mounia Slaoui, Abdelilah Berhili, Mohammed Bensalah, Rachid Seddik   +7 more
doaj   +1 more source

The factors affecting early death in newly diagnosed APL patients

Open Medicine, 2019
In the past, acute promyelocytic leukemia (APL) was considered as one of the most rapidly lethal form of acute myeloid leukemia (AML). The objective of this study was to assess clinical parameters affecting early death (ED) in patients with APL.
Ciftciler Rafiye, Haznedaroglu Ibrahim Celalettin, Aksu Salih, Ozcebe Osman, Sayınalp Nilgun, Malkan Umit Yavuz, Buyukasık Yahya   +6 more
doaj   +1 more source

Diagnosis and management of acute promyelocytic leukemia: Brazilian consensus guidelines 2024 on behalf of the Brazilian Association of Hematology, Hemotherapy and Cellular Therapy

Hematology, Transfusion and Cell Therapy
Improvements in clinical assessment have occurred since the last published recommendations on the diagnosis and treatment of acute promyelocytic leukemia in 2013.
Lorena Lobo de Figueiredo-Pontes, Luiz Fernando Bazzo Catto, Maria de Lourdes Lopes Ferrari Chauffaille, Katia Borgia Barbosa Pagnano, Maria Isabel Ayrosa Madeira, Elenaide Coutinho Nunes, Nelson Hamerschlak, Marcela Cavalcante de Andrade Silva, Thiago Xavier Carneiro, Teresa Cristina Bortolheiro, Tiago Thalles de Freitas, Rosane Isabel Bittencourt, Evandro Maranhão Fagundes, Eduardo Magalhães Rego   +13 more
doaj   +1 more source

Therapy-related myelodysplastic syndrome after successful treatment of acute promyelocytic leukemia: case report and literature review [PDF]

, 2017
Carmen M. Cirstea, Adriana Coliță, Bogdan Ionescu, Alexandra Ghiaur, Didona Vasilescu, Camelia Dobrea, Cerasela Jardan, Mihaela Dragomir, Anca Gheorghe, Zsofia Várady, Anca Roxana Lupu   +10 more
openalex   +1 more source

Pattern of Expression of PML-RARα Transcripts in Acute Promyelocytic Leukemia Patients and Its Correlation with Overall Survival: A Retrospective Study from Western India

Indian Journal of Medical and Paediatric Oncology
Introduction Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia with specific molecular pathogenesis, clinical features, and treatment. It is cytogenetically characterized by translocation t (15;17) (q24;q21).
Shweta Gondha, Prerna Walia, Beena Brahmbhatt, Jayendrakumar Patel, Toral Mandalia, Disha Jethva   +5 more
doaj   +1 more source

Routine use of microarray-based gene expression profiling to identify patients with low cytogenetic risk acute myeloid leukemia: accurate results can be obtained even with suboptimal samples

BMC Medical Genomics, 2012
Background Gene expression profiling has shown its ability to identify with high accuracy low cytogenetic risk acute myeloid leukemia such as acute promyelocytic leukemia and leukemias with t(8;21) or inv(16).
de la Blétière Diane Raingeard, Blanchet Odile, Cornillet-Lefèbvre Pascale, Coutolleau Anne, Baranger Laurence, Geneviève Franck, Luquet Isabelle, Hunault-Berger Mathilde, Beucher Annaelle, Schmidt-Tanguy Aline, Zandecki Marc, Delneste Yves, Ifrah Norbert, Guardiola Philippe   +13 more
doaj   +1 more source