Risk factors associated with early death, disease relapse and second primary malignancies in patients with newly diagnosed acute promyelocytic leukemia. [PDF]
Zhou DM +7 more
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Atypical single <i>PML</i>::<i>RARA</i> fusion in acute promyelocytic leukemia: mechanisms and clinical implications. [PDF]
Yang P +9 more
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Immune intervention is dispensable for retinoic acid/ arsenic therapy of murine acute promyelocytic leukemia. [PDF]
Esnault C +9 more
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The novel ETV6::RARA fusion gene, identified in acute promyelocytic leukemia, is sensitive to invitro all-tans retinoic acid and arsenic trioxide administrations. [PDF]
Hassani MA +8 more
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Nonbacterial Thrombotic Endocarditis as a Presenting Paraneoplastic Manifestation of Acute Promyelocytic Leukemia. [PDF]
Fradin JJ +4 more
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Acute Promyelocytic Leukemia Diagnosed Due to Pericoronitis: A Case Report. [PDF]
Yoshida Y +3 more
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Exploration of neuroprotective strategies in patients with acute promyelocytic leukemia complicated by cerebral hemorrhage. [PDF]
Hu J, Lai W.
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Significant advances have occurred in the diagnosis, treatment, and long-term outcome of patients with acute promyelocytic leukemia (APL). The purpose of this review is to describe the molecular genetics of this disease, the use of all-trans retinoic acid (ATRA) in clinical trials of APL, and the clinical and basic research questions for future ...
R S, Lemons +6 more
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AbstractAcute promyelocytic leukemia (APL) is characterized by proliferation of morphologically abnormal promyelocytes and a severe bleeding diathesis. The abnormal promyelocyte is characterized by abundant, large granules, many of which are spindle‐shaped. Electron microscopic appearance of the granules closely resembles that of Auer rods.
J, Groopman, L, Ellman
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