Results 1 to 10 of about 96,549 (135)

Arsenic Trioxide Impacts Viral Latency and Delays Viral Rebound after Termination of ART in Chronically SIV‐Infected Macaques

open access: yesAdvanced Science, 2019
The latent viral reservoir is the source of viral rebound after interruption of antiretroviral therapy (ART) and is the major obstacle in eradicating the latent human immunodeficiency virus‐1 (HIV‐1).
Qing Yang   +16 more
doaj   +1 more source

Addition of Arsenic Trioxide into Induction Regimens Could Not Accelerate Recovery of Abnormality of Coagulation and Fibrinolysis in Patients with Acute Promyelocytic Leukemia. [PDF]

open access: yesPLoS ONE, 2016
AIM:All-trans retinoic acid combined to anthracycline-based chemotherapy is the standard regimen of acute promyelocytic leukemia. The advent of arsenic trioxide has contributed to improve the anti-leukemic efficacy in acute promyelocytic leukemia.
Ye Zhang   +4 more
doaj   +1 more source

Arsenic trioxide as a novel anti-glioma drug: a review

open access: yesCellular & Molecular Biology Letters, 2020
Arsenic trioxide has shown a strong anti-tumor effect with little toxicity when used in the treatment of acute promyelocytic leukemia (APL). An effect on glioma has also been shown.
Yi Fang, Zhen Zhang
doaj   +1 more source

Osteonecrosis of the jaw induced by arsenic trioxide therapy in acute promyelocytic leukemia patient: a case report and literature review

open access: yes口腔疾病防治, 2023
Objective To investigate the etiology, clinical manifestations, treatment and prevention of jaw necrosis caused by arsenic trioxide to provide a reference for clinical diagnosis and treatment.
WANG Liping   +2 more
doaj   +1 more source

Arsenic Trioxide Compound Modulates Multiple Myeloma Phenotypes: Assessment on Cell Line Models [PDF]

open access: yesIranian Journal of Public Health, 2006
Recent evidences suggest that multiple myeloma phenotypes (MMPs) are involved in the infiltration of multiple myeloma-affected marrow foci. In this study, the effects of arsenic trioxide on the invasive and angiogenic phenotypes of multiple myeloma (MM ...
MR Khorramizadeh   +9 more
doaj   +1 more source

Relapsed acute promyelocytic leukemia in a hemodialysis-dependent patient treated with arsenic trioxide: a case report

open access: yesJournal of Medical Case Reports, 2012
Introduction In the relapsed setting, arsenic trioxide remains the backbone of treatment. Scant literature exists regarding treatment of relapsed acute promyelocytic leukemia in patients with renal failure.
Emmons Gregory S   +3 more
doaj   +1 more source

Treatment of new cases of Acute Promyelocytic Leukemia With Arsenic Trioxide [PDF]

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2005
Introduction: Arsenic Trioxide is effective and approved for treatment of relapsed or refractory APL cases to ATRA but its effects in new cases of APL is not clear and needs long term follow up to dis¬close the role of this drug in treatment of APL in ...
Ardeshir Ghavamzadeh   +12 more
doaj   +1 more source

Gingival and localized alveolar bone necrosis related to the use of arsenic trioxide paste—Two case reports

open access: yesJournal of the Formosan Medical Association, 2014
The leakage of arsenic trioxide paste from tooth fillings has been associated with widespread necrosis of the supporting periodontal tissues. This report describes two cases of arsenic trioxide paste-induced gingival and localized alveolar bone necrosis ...
Gin Chen, Po-Ta Sung
doaj   +1 more source

Oral arsenic trioxide ORH-2014 pharmacokinetic and safety profile in patients with advanced hematologic disorders

open access: yesHaematologica, 2020
Daily intravenous arsenic trioxide administered with all-trans retinoid acid, the standard-of-care for acute promyelocytic leukemia, is costly and challenging to administer.
Farhad Ravandi   +13 more
doaj   +1 more source

Effect of arsenic trioxide (Trisenox) on actin organization in K-562 erythroleukemia cells.

open access: yesFolia Histochemica et Cytobiologica, 2010
Actin is one of the cytoskeletal proteins that take part in many cellular processes. The aim of this study was to show the influence of Trisenox (arsenic trioxide), on the cytoplasmic and nuclear F-actin organization. Arsenic trioxide is the proapoptotic
Dariusz Grzanka   +4 more
doaj   +1 more source

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