Results 61 to 70 of about 22,947 (145)

Acute promyelocytic leukemia presenting with features of metastatic osseous disease

Leukemia Research Reports, 2018
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia defined by a balanced translocation between chromosomes 15 and 17 resulting in fusion of the promyelocytic leukemia gene (PML) on chromosome 15 with the retinoic acid ...
Carmen Winters, Andy I. Chen, Stephen Moore, Elie Traer, Jennifer Dunlap   +4 more
doaj   +1 more source

CCNE1: A Cell Cycle Regulator That Influences Tumor Progression

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACTCyclin E1 (CCNE1), a pivotal member of the cyclin family, governs the G1/S phase transition of the cell cycle by binding to and activating cyclin‐dependent kinase 2 (CDK2), thereby initiating DNA replication and driving S‐phase entry. In a broad spectrum of human malignancies—including breast, ovarian, gastric, and non‐small cell lung cancers ...
Liang Yan, Siyi Liu, Yanling Li, Qian He, Chen Long, Ning Tang, Yanhong Zhou   +6 more
wiley   +1 more source

Acute promyelocytic leukemia in a patient with chronic lymphocytic leukemia-A case report

Hematology/Oncology and Stem Cell Therapy, 2019
Chronic lymphocytic leukemia (CLL) is known to be associated rarely with myeloid malignancies such as acute myelogenous leukemia. In this article, we report an extremely rare occurrence of acute promyelocytic leukemia in a patient with CLL. A 71-year-old
Prajwal Boddu, Ellen Schlette, Beenu Thakral, Guillin Tang, Naveen Pemmaraju, Tapan Kadia, Alessandra Ferrajoli, Farhad Ravandi, William Wierda, Nitin Jain   +9 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Central Nervous System Double Relapse of Acute Promyelocytic Leukemia and Acute Myelomonocytic Leukemia

Case Reports in Hematology, 2019
Relapse of acute promyelocytic leukemia (APL) and non-M3-acute myeloid leukemia in the central nervous system (CNS) are rare events. Here, we describe a case of simultaneous relapses of APL and acute myelomonocytic leukemia on the CNS of a patient after ...
Laura M. Stanko, Vishnu Reddy, Fady M. Mikhail, Nikolaos Papadantonakis   +3 more
doaj   +1 more source

Risk Adjustment in the Medicare Advantage Population Using Encounter Data

Health Services Research, Volume 61, Issue 5, October 2026.
ABSTRACT Objective To estimate the Centers for Medicare and Medicaid Services (CMS) Hierarchical Condition Category (HCC) risk model using Medicare Advantage (MA) encounter data, as an initial step toward recalibrating risk‐adjusted MA payments. Data Sources and Study Setting A 20% sample of Traditional Medicare (TM) claims and MA encounter data for ...
Caroline S. Carlin, Roger Feldman, Jeah Jung   +2 more
wiley   +1 more source

Assessment of the Performance of Siemens Scopio Digital Morphology on Bone Marrow Aspirates in Onco‐Hematology

International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1000-1007, October 2026.
ABSTRACT Objectives Digital morphology (DM) systems assisted by artificial intelligence are increasingly being introduced into hematology laboratories; however, data on their performance in routine clinical practice for bone marrow aspirates (BMA) remain limited.
Gina Zini, John Marra, Elena Rossi, Silvia Bellesi, Nicoletta Pelliccioni, Giuseppe d'Onofrio, Patrizia Chiusolo   +6 more
wiley   +1 more source

Acute Promyelocytic Leukemia Complicated by Deep Venous Thrombosis, Pulmonary Thromboembolism, and Hematemesis

Indian Journal of Clinical Cardiology
Acute promyelocytic leukemia (APML) is a myeloid leukemia classified as M3-AML. It is known for its bleeding diathesis, which is predominantly driven by disseminated intravascular coagulation and primary hyperfibrinolysis.
Sudipta Mondal, Saurav Banerjee
doaj   +1 more source

Allogeneic stem cell transplantation for advanced acute promyelocytic leukemia in the ATRA and ATO era

Haematologica, 2012
The role of allogeneic stem cell transplant in advanced acute promyelocytic leukemia patients who received standard first- and second-line therapy is still unknown.
Safaa M. Ramadan, Ambra Di Veroli, Agnese Camboni, Massimo Breccia, Anna Paola Iori, Franco Aversa, Luca Cupelli, Cristina Papayannidis, Andrea Bacigalupo, William Arcese, Francesco Lo-Coco   +10 more
doaj   +1 more source

Acute lower limb ischemia revealing hypo granular acute promyelocytic leukemia

Leukemia Research Reports
Introduction: Acute promyelocytic leukemia (AML-M3), classified as acute Myeloid leukemia with PML RARA according to the 5th edition of the World Health Organization classification of haematolymphoid tumors 2022 [1], is marked by abnormal promyelocyte ...
Sabrina Belmahi, Zainab Kajeiou, Loubna Yacoubi, Noussaiba Azzi, Mounia Slaoui, Abdelilah Berhili, Mohammed Bensalah, Rachid Seddik   +7 more
doaj   +1 more source