Results 51 to 60 of about 3,409,620 (281)

Linear Association Between Hypoalbuminemia and Increased Risk of Acute Respiratory Distress Syndrome in Critically Ill Adults

Critical Care Explorations, 2021
OBJECTIVES:. We hypothesized that low serum albumin would contribute to pulmonary edema formation, thereby independently increasing the risk of developing acute respiratory distress syndrome in critically ill patients. DESIGN:.
J. Brennan McNeil, MS, Karen E. Jackson, MD, Chunxue Wang, PhD, Edward D. Siew, MD, Andrew J. Vincz, AA, Ciara M. Shaver, MD, PhD, Julie A. Bastarache, MD, Lorraine B. Ware, MD   +7 more
doaj   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS

Respiratory Research, 2021
We identified a novel microRNA biomarker panel consisting of 6 microRNAs predicting mortality in pediatric acute respiratory distress syndrome patients.
Lisa K. Lee, Mansoureh Eghbali, Anil Sapru   +2 more
doaj   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Sigh in Acute Respiratory Distress Syndrome [PDF]

American Journal of Respiratory and Critical Care Medicine, 1999
Abstract Mechanical ventilation with plateau pressure lower than 35 cm H2O and high positive end-expiratory pressure (PEEP) has been recommended as lung protective strategy. Ten patients with ARDS (five from pulmonary [p] and five from extrapulmonary [exp] origin), underwent 2 h of lung protective strategy, 1 h of lung protective ...
P. Pelosi, P. Cadringher, N. Bottino, M. Panigada, F. Carrieri, E. Riva, A. Lissoni, L. Gattinoni   +7 more
openaire   +3 more sources

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Acute Cor Pulmonale in COVID-19-Related ARDS

JACC: Case Reports, 2020
Coronavirus disease-19 (COVID-19)-related severe acute respiratory distress syndrome can lead to acute cor pulmonale. We report a case of acute cor pulmonale secondary to severe COVID-19 acute respiratory distress syndrome diagnosed with transesophageal ...
Pierre Huette, MD, Christophe Beyls, MD, Mathieu Guilbart, MD, Guillaume Haye, MD, Fatim-Zahra Najid, MD, Benjamin Mestan, MD, Pierre-Alexandre Roger, MD, Hervé Dupont, MD, PhD, Osama Abou-Arab, MD, PhD, Yazine Mahjoub, MD, PhD   +9 more
doaj   +1 more source

Simvastatin in the Acute Respiratory Distress Syndrome [PDF]

New England Journal of Medicine, 2014
BACKGROUND Studies in animals and in vitro and phase 2 studies in humans suggest that statins may be beneficial in the treatment of the acute respiratory distress syndrome (ARDS). This study tested the hypothesis that treatment with simvastatin would improve clinical outcomes in patients with ARDS.
McAuley, Daniel F., Laffey, John G., O'Kane, Cecilia M., Perkins, Gavin D., Mullan, Brian, Trinder, T. John, Johnston, Paul, Hopkins, Philip A., Johnston, Andrew J., McDowell, Cliona, McNally, Christine   +10 more
openaire   +5 more sources

Recruitment manoeuvres in acute respiratory distress syndrome: Little evidence for routine use [PDF]

, 2013
Acutely injured lungs consist of heterogeneous regions of aerated and collapsed alveoli. Implementation of alveolar recruitment manoeuvres (RMs) for the management hypoxemic respiratory failure, however, has been controversial.
Oliver Poole
core  

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source