Results 71 to 80 of about 197,590 (253)

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection

Einstein (São Paulo)
In December 2019, a series of patients with severe pneumonia were identified in Wuhan, Hubei province, China, who progressed to severe acute respiratory syndrome and acute respiratory distress syndrome.
Thiago Domingos Corrêa, Gustavo Faissol Janot de Matos, Bruno de Arruda Bravim, Ricardo Luiz Cordioli, Alejandra del Pilar Gallardo Garrido, Murillo Santucci Cesar de Assuncao, Carmen Silvia Valente Barbas, Karina Tavares Timenetsky, Roseny dos Reis Rodrigues, Hélio Penna Guimarães, Roberto Rabello Filho, Frederico Polito Lomar, Farah Christina de La Cruz Scarin, Carla Luciana Batista, Adriano José Pereira, João Carlos de Campos Guerra, Bárbara Vieira Carneiro, Ricardo Kenji Nawa, Rodrigo Martins Brandão, Antônio Eduardo Pereira Pesaro, Moacyr Silva Júnior, Fabricio Rodrigues Torres de Carvalho, Cilene Saghabi de Medeiros Silva, Ana Claudia Ferraz de Almeida, Marcelo Franken, Marcele Liliane Pesavento, Raquel Afonso Caserta Eid, Leonardo José Rolim Ferraz   +27 more
doaj   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Comparative Hemodynamic Effects of BiPAP and APRV in Patients with ARDS: A Systematic Review

Albanian Journal of Trauma and Emergency Surgery
Introduction: Positive pressure ventilation is key in the treatment of patients with acute respiratory distress syndrome. Bilevel Positive Airway Pressure and Airway Pressure Release Ventilation modalities aim to improve oxygenation and reduce lung ...
Leon Hajdari, Egzon Daku, Gramoz Bunjaku, Basri Lenjani, Dardan Lenjani   +4 more
doaj   +1 more source

Identification of antibiotic allergies in children using prescribing patterns in the electronic medical record

British Journal of Clinical Pharmacology, EarlyView.
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis, Kailey Tang, Renee Dimond, Alice Lei, Amanda Wilkins, Amanda Gwee   +5 more
wiley   +1 more source

COVID-19-associated acute respiratory distress syndrome versus classical acute respiratory distress syndrome (a narrative review)

Iranian Journal of Microbiology, 2021
Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus, Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), led to the ongoing global public health crisis.
Inna Krynytska, Mariya Marushchak, Inna Birchenko, Alina Dovgalyuk, Oleksandr Tokarskyy   +4 more
doaj  

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

Epileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef   +10 more
wiley   +1 more source

Controvérsias acerca da acidose hipercápnica na síndrome do desconforto respiratório agudo Controversies involving hypercapnic acidosis in acute respiratory distress syndrome

Revista Brasileira de Terapia Intensiva, 2009
A síndrome do desconforto respiratório agudo é caracterizada por uma reação inflamatória difusa do parênquima pulmonar induzida por um insulto direto ao epitélio alveolar (síndrome do desconforto respiratório agudo pulmonar) ou indireto por meio do ...
Liliane Nardelli, Patricia Rieken Macedo Rocco, Cristiane Sousa Nascimento Baez Garcia   +2 more
doaj   +1 more source

Disseminaded coccidiodomycosis presentig as acute respiratory distress syndrome in a liver postrasplant recipient

Infectio, 2021
Acute respiratory distress syndrome (ARDS) is a respiratory process of acute onset, showing on X rays as bilateral pulmonary infiltrates and severe respiratory failu-re, Coccidiodomycosis is a unusual cause of acute respiratory distress syndrome, the ...
Darwin Lambraño-Castillo
doaj   +1 more source

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze, Robyn Whitney, Dorothée Ville, Nathalie Villeneuve, Anna‐Maria Hartmann, Lisa Becker, Jens Hausmann, Jinwei Zhang, Cathy Brier, Lucie I. Pisella, Perrine Friedel, Audrey Labalme, Eudeline Alix, Nicolas Chatron, Damien Sanlaville, Sylvie Gory‐Fauré, Eric Denarier, Christophe Porcher, Gaetan Lesca, Igor Medina   +19 more
wiley   +1 more source