Acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) is a common diagnosis among children admitted to pediatric intensive care units. This heterogeneous disorder has numerous pulmonary and non-pulmonary causes and is associated with a significant risk of mortality. Many supportive therapies exist for ARDS. SEARCH: Literature search was performed by using the key
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Sigh in Acute Respiratory Distress Syndrome [PDF]
Mechanical ventilation with plateau pressure lower than 35 cm H2O and high positive end-expiratory pressure (PEEP) has been recommended as lung protective strategy. Ten patients with ARDS (five from pulmonary [p] and five from extrapulmonary [exp] origin), underwent 2 h of lung protective strategy, 1 h of lung protective strategy with three consecutive
P. Pelosi +7 more
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Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel +12 more
wiley +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Acquired agitation in acute respiratory distress syndrome with COVID-19 compared to influenza patients: a propensity score matching observational study [PDF]
Adel Maamar +11 more
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Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
Correlation Between the Ratio of Oxygen Saturation to Fraction of Inspired Oxygen and the Ratio of Partial Pressure of Oxygen to Fraction of Inspired Oxygen in Detection and Risk Stratification of Pediatric Acute Respiratory Distress Syndrome [PDF]
Pooja D Lohano +5 more
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The Effect of Voluntary Staying at Home on Japanese Female Suicide During the COVID‐19 Pandemic
ABSTRACT In Japan, female suicide increased during the COVID‐19 pandemic. This study evaluated how pandemic‐related home confinement affected female suicide. We employed a shift‐share instrumental variable design to assess whether differential exposure to the pandemic caused changes in suicide incidence.
Yoko Ibuka +3 more
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Methylprednisolone Treatment Versus Standard Supportive Care for Adult COVID-19 Mechanically Ventilated, Acute Respiratory Distress Syndrome Patients [PDF]
Masood ur Rahman +9 more
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Abstract Objective This study aimed to investigate maternal and neonatal outcomes of pregnancies complicated by pre‐eclampsia (PE) in Indonesia and analyze regional variations in risk factors and clinical outcomes across the country. Methods A multicenter retrospective cohort study was conducted in 30 hospitals located across five major islands in ...
Muhammad Ilham Aldika Akbar +49 more
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