Results 41 to 50 of about 87,305 (225)

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

CAUSES OF RESPIRATORY DISTRESS IN CHILDREN [PDF]

Acta Medica Iranica, 2008
"nThere is a lack of large, prospective epidemiologic studies concerning acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in pediatric population.
M M Karambin, H Hashemian
doaj   +2 more sources

Disseminaded coccidiodomycosis presentig as acute respiratory distress syndrome in a liver postrasplant recipient

Infectio, 2021
Acute respiratory distress syndrome (ARDS) is a respiratory process of acute onset, showing on X rays as bilateral pulmonary infiltrates and severe respiratory failu-re, Coccidiodomycosis is a unusual cause of acute respiratory distress syndrome, the ...
Darwin Lambraño-Castillo
doaj   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

Progress in cytokine research for ARDS: A comprehensive review

Open Medicine
Acute respiratory distress syndrome (ARDS) is a critical form of acute respiratory failure characterized by diffuse alveolar damage, refractory hypoxemia, and non-cardiogenic pulmonary edema, resulting in high mortality. Dysregulated inflammation, driven
Zhou Kaihuan, Lu Junyu
doaj   +1 more source

Progress in diagnosis and treatment of high-altitude acute respiratory distress syndrome

Di-san junyi daxue xuebao, 2019
Acute respiratory distress syndrome (ARDS) is a common but critical respiratory condition with high morbidity and mortality rates. Despite its many similarities with ARDS seen in plain regions, ARDS that occurs in high-altitude regions has specific ...
MA Siqing, LUO Yongjun
doaj   +1 more source

Acute respiratory distress syndrome relapsing in 10 months with an initial manifestation of polymyositis

Clinical Case Reports, 2021
Autoimmune disorders are an important cause of acute respiratory distress syndrome (ARDS). We report a case of a patient with steroid‐responsive ARDS that relapsed in 10 months with an initial manifestation of seronegative polymyositis.
Yukihisa Takeda, Mariko Ono, Hayato Kinoshita, Yoko Nagatomo, Hiroki Miyauchi, Hiroshi Tsukamoto, Hiroyuki Nakamura, Kazutetsu Aoshiba   +7 more
doaj   +1 more source

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng, Wen Gao, Jonathan Do, Danli Lu, Ying‐Wei Lan, Andreas Damianos, Gautam Verma, Ali Al Siraj, Isabella Lowry, Lance Peter, Nicholas E. Banovich, Fei Sun, Hua He, Tanya V. Kalin, Vladimir V. Kalinichenko   +14 more
wiley   +1 more source

Aerosolized prostacyclins for acute respiratory distress syndrome (ARDS) [PDF]

Cochrane Database of Systematic Reviews, 2017
Acute respiratory distress syndrome (ARDS) is a critical condition that is associated with high mortality and morbidity. Aerosolized prostacyclin has been used to improve oxygenation despite the limited evidence available so far.This review was originally published in 2010 and updated in 2017.To assess the benefits and harms of aerosolized prostacyclin
Arash, Afshari, Anders, Bastholm Bille, Mikkel, Allingstrup   +2 more
openaire   +2 more sources

Preoperative FIB‐4 Index as a Potential Factor Associated With Severe Postoperative Complications and Endogenous Organ Failure After Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrates that a preoperative FIB‐4 index ≥ 5.0 independently predicts severe complications and endogenous organ failure (EOF) following hepatectomy for hepatocellular carcinoma. By capturing structural liver fragility and systemic vulnerability, the FIB‐4 index enhances surgical risk stratification beyond traditional functional markers ...
Masanori Nakamura, Yukiyasu Okamura, Osamu Aramaki, Nao Yoshida, Yusuke Mitsuka, Hayato Abe, Shunsuke Yamagishi, Yasuhiro Okumura, Kyongsun Pak, Shinobu Masuda   +9 more
wiley   +1 more source