Results 51 to 60 of about 3,524,865 (247)
Frontiers in Medicine, 2023 IntroductionPatients suffering from severe acute respiratory distress syndrome (ARDS) are usually treated with mechanical ventilation. Extracorporeal membrane oxygenation (ECMO) has traditionally been considered a life-saving therapy and was reserved as ...
Qinglin Wu +3 more
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Advanced Science, EarlyView.Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng +14 more
wiley +1 more source
Advanced Science, EarlyView.LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang +12 more
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Targeting Neutrophils to Treat Acute Respiratory Distress Syndrome in Coronavirus Disease
Frontiers in Pharmacology, 2020 This review describes targeting neutrophils as a potential therapeutic strategy for acute respiratory distress syndrome (ARDS) associated with coronavirus disease 2019 (COVID-19), a pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-
Chih-Chao Chiang +12 more
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Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium
Advanced Science, EarlyView.Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed +12 more
wiley +1 more source
CAUSES OF RESPIRATORY DISTRESS IN CHILDREN [PDF]
Acta Medica Iranica, 2008 There is a lack of large, prospective epidemiologic studies concerning acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in pediatric population.
M Karambin, H Hashemian
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Clinical Case Reports, 2021 Autoimmune disorders are an important cause of acute respiratory distress syndrome (ARDS). We report a case of a patient with steroid‐responsive ARDS that relapsed in 10 months with an initial manifestation of seronegative polymyositis.
Yukihisa Takeda +7 more
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ARDS: Acute Respiratory Distress Syndrome [PDF]
, 2016 The purpose of this poster presentation is to discuss and examine the medical condition known as acute respiratory distress syndrome (ARDS). The presentation will include a review of the epidemiology, pathophysiology and etiologies of ARDS, as well as ...
Lobacz, Jeffrey
core
Extracorporeal Life Support for Patients with Acute Respiratory Distress Syndrome: Review
, 2015 Patients with severe acute respiratory distress syndrome (ARDS) is an acute diffuse, inflammatory lung injury, leading to increased pulmonary vascular permeability with hypoxemia and bilateral radiographic opacities, associated with decreased lung ...
Tülin Akarsu Ayazoğlu, Didem Onk
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Advanced Science, EarlyView.During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu +14 more
wiley +1 more source