Results 41 to 50 of about 471,041 (312)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Preprocedural D-Dimer Level as a Predictor of First-Pass Recanalization and Functional Outcome in Endovascular Treatment of Acute Ischemic Stroke [PDF]

, 2023
Jang‐Hyun Baek, Ji Hoe Heo, Hyo Suk Nam, Byung Moon Kim, Dong Joon Kim, Young Dae Kim   +5 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

National Incidence of Intracranial Haemorrhage–Related Hospitalisations and Mortality in England 2014–2019

Stroke Research and Treatment
Conclusion: The majority of ICrH acute hospitalisations (59.7%) were atraumatic. Sex differences were seen in outcome measurements: males had a higher overall incidence of hospitalisation; however, females had a higher incidence of atraumatic ICrH ...
Katherine J. Creeper, Andrew C. Stafford, Allycia MacDonald, Arvind Chandratheva, Alexander T. Cohen   +4 more
doaj   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Transitioning to home and beyond following stroke: a prospective cohort study of outcomes and needs

BMC Health Services Research
Introduction Understanding of the needs of people with stroke at hospital discharge and in the first six-months is limited. This study aim was to profile and document the needs of people with stroke at hospital discharge to home and thereafter. Methods A
Geraldine O’Callaghan, Martin Fahy, Sigrid O’Meara, Mairead Chawke, Eithne Waldron, Marie Corry, Sinead Gallagher, Catriona Coyne, Julie Lynch, Emma Kennedy, Thomas Walsh, Hilary Cronin, Niamh Hannon, Clare Fallon, David J Williams, Peter Langhorne, Rose Galvin, Frances Horgan   +17 more
doaj   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Measures of intracranial compartments in acute intracerebral haemorrhage: data from the Rapid Intervention with Glyceryl Trinitrate in Hypertensive Stroke-2 Trial (RIGHT-2)

Stroke and Vascular Neurology
Background and purpose Intracerebral haemorrhage volume (ICHV) is prognostically important but does not account for intracranial volume (ICV) and cerebral parenchymal volume (CPV).
Joanna M Wardlaw, Philip M Bath, Lisa J Woodhouse, Nikola Sprigg, Zhe Kang Law, Kailash Krishnan, Rob A Dineen   +6 more
doaj   +1 more source

Demographic, clinical and radiological characteristics of patients with acute ischemic stroke and acute symptomatic seizures [PDF]

Medicinski Podmladak
Introduction: A growing number of stroke survivors face various stroke complications, including acute symptomatic seizures. Symptomatic seizures are associated with longer hospitalizations, negative functional outcomes, and lower quality of life for ...
Baljak Anja, Kovačević Maša
doaj   +1 more source