Results 1 to 10 of about 786,429 (286)

Acute and sub-acute toxicity assessment of methanolic stem bark extract of Khaya anthotheca (Meliaceae) in Wistar rats [PDF]

Tropical Medicine and Health
Background Khaya anthotheca (Meliaceae) is a medicinal plant with a wide range of therapeutic properties attributable mainly to the diverse limonoids it contains.
Betty Akwongo, Esezah K. Kakudidi, Anthony M. Nsubuga, Morgan Andama, Mary Namaganda, Patience Tugume, Savina Asiimwe, Godwin Anywar, Esther Katuura   +8 more
doaj   +2 more sources

Evaluation of the in vivo and in vitro safety profile of Cuscuta epithymum ethanolic extract [PDF]

Avicenna Journal of Phytomedicine, 2021
Objective: Cuscuta epithymum (CE) is one of the most popular medicinal plants in the world. However, detailed information about its toxicity is not available.
Mohammad Reza Abedini, Samaneh PAki, Mahtab Mohammadifard, Mohsen Foadoddini, Khadijeh Vazifeshenas-Darmiyan, Mehran Hosseini   +5 more
doaj   +1 more source

Proton Therapy of Prostate and Pelvic Lymph Nodes for High Risk Prostate Cancer: Acute Toxicity [PDF]

International Journal of Particle Therapy, 2021
Purpose: To assess acute gastrointestinal (GI) and genitourinary (GU) toxicities of intensity-modulated proton therapy (IMPT) targeting the prostate/seminal vesicles and pelvic lymph nodes for prostate cancer.
Richard Choo, MD, David W. Hillman, MS, Thomas Daniels, MD, Carlos Vargas, MD, Jean Claude Rwigema, MD, Kimberly Corbin, MD, Sameer Keole, MD, Sujay Vora, MD, Kenneth Merrell, MD, Bradley Stish, MD, Thomas Pisansky, MD, Brian Davis, MD, PhD, Adam Amundson, William Wong, MD   +13 more
doaj   +1 more source

Evaluation of the Acute and Sub-Acute Oral Toxicity of Jaranol in Kunming Mice

Frontiers in Pharmacology, 2022
Background: Jaranol has shown a wide range of pharmacological activities; however, no study has yet examined in vivo toxicity. The study aimed to investigate the oral acute and sub-acute toxicity of jaranol in mice.Methods: The acute toxicity was ...
Tianlong Liu, Yao Zhang, Jing Liu, Junwen Peng, Xin Jia, Xin Jia, Xin Jia, Yunfeng Xiao, Yunfeng Xiao, Lanbing Zheng, Yu Dong, Yu Dong   +11 more
doaj   +1 more source

Acute Methylenedioxypyrovalerone Toxicity [PDF]

Journal of Medical Toxicology, 2014
The objective of this study was to characterize the acute clinical effects, laboratory findings, complications, and disposition of patients presenting to the hospital after abusing synthetic cathinone. We conducted a retrospective multicenter case series of patients with synthetic cathinone abuse by searching for the terms bath salts, MDPV ...
Blake A, Froberg, Michael, Levine, Michael C, Beuhler, Bryan S, Judge, Philip W, Moore, Kristin M, Engebretsen, Nathanael J, Mckeown, Christopher D, Rosenbaum, Amy C, Young, Daniel E, Rusyniak   +9 more
openaire   +2 more sources

PredAOT: a computational framework for prediction of acute oral toxicity based on multiple random forest models

BMC Bioinformatics, 2023
Background Acute oral toxicity of drug candidates can lead to drug development failure; thus, predicting the acute oral toxicity of small compounds is important for successful drug development.
Jae Yong Ryu, Woo Dae Jang, Jidon Jang, Kwang-Seok Oh   +3 more
doaj   +1 more source

Interspecies Quantitative Structure-Toxicity-Toxicity Relationships for Predicting the Acute Toxicity of Organophosphorous Compounds

Chemistry Proceedings, 2021
Median lethal concentration values are commonly used to express the relative risk related to the acute toxicity of chemicals. In this paper, we considered rat and mouse acute toxicity (LD50) data of organophosphorous compounds (OPs) with diverse ...
Gheorghe Ilia, Ana Borota, Simona Funar-Timofei   +2 more
doaj   +1 more source

Assessment of acute and sub-acute toxicity of olive pomace in female Wistar rats [PDF]

World Cancer Research Journal, 2022
Objective: Olive Pomace (OP) is considered to be a rich source of phenolic compounds. Recently many researches showed a broad biological activity of this by-product of the olive oil production process in addition to their emergence as value-added ...
Z. Badi, B. Guermouche, N. Haddam, N. Belyagoubi, K. Rouigueb, H. Benzerjeb, M. Dali-Sahi, Y. Kachekouche, H. Merzouk   +8 more
doaj   +1 more source

Toxicity Profile of Imrt Vs. 3D-Crt in Head and Neck Cancer: A Retrospective Study [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Role of radiotherapy in comprehensive management of head and neck cancer for achieving tumour control and organ preservation is now well established and radiotherapy is routinely used in adjuvant setting after surgery, concurrently with
Gopa Ghosh, Ramanjis Tallari, Anupam Malviya   +2 more
doaj   +1 more source

Acute and late toxicity patterns of moderate hypo-fractionated radiotherapy for prostate cancer: A systematic review and meta-analysis

Clinical and Translational Radiation Oncology, 2023
Introduction: Moderate hypofractionated (HF) radiotherapy is becoming the new standard in radiotherapy for prostate cancer patients. It is established as safe, but it might be associated with increased acute toxicity levels.
F. Sinzabakira, V. Brand, W.D. Heemsbergen, L. Incrocci   +3 more
doaj   +1 more source