Results 111 to 120 of about 4,781,689 (344)

High-Dose (80 Gy) Intensity-Modulated Radiation Therapy with Daily Image-Guidance as Primary treatment for Localized Prostate Cancer [PDF]

open access: yes, 2018
: Purpose: : To report acute and late toxicity in prostate cancer patients treated by high-dose intensity-modulated radiation therapy (IMRT) with daily image-guidance.
Aebersold, Daniel   +6 more
core  

A Case of Digoxin Toxicity Due to Acute Renal Failure [PDF]

open access: diamond, 2021
Stephanie Digiovanni-Kinsley   +3 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Acute toxicity studies of the South African medicinal plant Galenia africana

open access: yesToxicology Reports, 2018
Background: Medicinal plants are used by a large proportion of the global population as complementary and alternative medicines. However, little is known about their toxicity. G.
Tiza Ng’uni   +2 more
doaj   +1 more source

ProTox-II: a webserver for the prediction of toxicity of chemicals

open access: yesNucleic Acids Res., 2018
Advancement in the field of computational research has made it possible for the in silico methods to offer significant benefits to both regulatory needs and requirements for risk assessments, and pharmaceutical industry to assess the safety profile of a ...
Priyanka Banerjee   +3 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Acute methotrexate toxicity due to overdosing in psoriasis: A series of seven cases

open access: yesIndian Dermatology Online Journal, 2019
Overdosing is the major cause of acute methotrexate toxicity in psoriasis patients. There are no published data regarding the acute cumulative dose causing acute toxicity, duration to achieve acute cumulative toxic dose and various reasons for wrong ...
Swetalina Pradhan   +4 more
doaj   +1 more source

Comparison Between Acute Toxicity And Chemical Analysis Of Natural Gas Drilling Effluent Samples Using Penaeus Monodon [PDF]

open access: yes, 2011
The regulation of point source discharges usually based on specific chemicals which describe thresholds below which no adverse impact on the receiving water.
Diamond, J. (Jerry)   +3 more
core   +1 more source

Wild bee toxicity data for pesticide risk assessments [PDF]

open access: yes, 2019
Pollination services are vital for agriculture, food security and biodiversity. Although many insect species provide pollination services, honeybees are thought to be the major provider of this service to agriculture. However, the importance of wild bees
Lewis, Kathleen, Tzilivakis, John
core   +2 more sources

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