Results 31 to 40 of about 786,429 (286)

An Assessment of the Oral and Inhalation Acute Toxicity of Nickel Oxide Nanoparticles in Rats

open access: yesNanomaterials, 2023
Nickel oxide nanoparticles (NiO NPs) have been the focus of many toxicity studies. However, acute toxicity studies that identify toxicological dose descriptors, such as an LC50 or LD50, are lacking.
Tara Lyons-Darden   +6 more
doaj   +1 more source

Proton beam therapy delivered using pencil beam scanning vs. passive scattering/uniform scanning for localized prostate cancer: Comparative toxicity analysis of PCG 001-09

open access: yesClinical and Translational Radiation Oncology, 2019
Background and purpose: Patient-level benefits of proton beam therapy (PBT) relative to photon therapy for prostate cancer (PC) continue to be the focus of debate. Although trials comparing the two modalities are underway, most are being conducted using “
Mark V. Mishra   +11 more
doaj   +1 more source

Preliminary studies of acute and sub-chronic toxicity of the aqueous extract of Guibourtia tessmannii (Harms) J. Leonard stem barks (Caesalpiniaceae) in mice and rats

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2016
Objective: To investigate the toxicity of aqueous extract of Guibourtia tessmannii (Harms) J. Leonard (G. tessmannii) and evaluate its safety. Methods: NMRI mice were used to determine the acute toxicity of G. tessmannii. Increasing concentrations of the
Noreen Orianna Koumba Madingou   +6 more
doaj   +1 more source

Challenges for the development of a biotic ligand model predicting copper toxicity in estuaries and seas [PDF]

open access: yes, 2012
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 SETAC.An effort is ongoing to develop a biotic ligand model (BLM) that predicts copper (Cu) toxicity in estuarine and marine ...
de Polo, A, Scrimshaw, MD
core   +1 more source

Safety assessment of AYUSH-64 through acute and 90-days repeated dose oral toxicity

open access: yesInternational Journal of Ayurveda Research, 2023
Background: AYUSH-64 is a polyherbal Ayurvedic antimalarial formulation, also found effective in COVID-19. Aim: The present study was designed to investigate the safety of AYUSH-64 in acute and 90-day repeated dose oral toxicity as per the Organization ...
Srikanth Ala   +4 more
doaj   +1 more source

Study of Acute Toxicity of a New Veterinary Drug for Inttrammary Introduction [PDF]

open access: yes, 2018
Preclinical studies of veterinary medicinal products are important and compulsory studies in the development of new dosage forms. The aim of preclinical research is to determine the toxic effect and therapeutic efficacy of the test substance-the future ...
Polova, Z. (Zhanna)
core  

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra   +3 more
wiley   +1 more source

A retrospective analysis of honey bee (Apis mellifera) pesticide toxicity data.

open access: yesPLoS ONE, 2022
Current USEPA ecological risk assessments for pesticide registration include a determination of potential risks to bees. Toxicity data are submitted to support these assessments and the USEPA maintains a large database containing acute and chronic ...
Frank T Farruggia   +13 more
doaj   +1 more source

Adverse reactions of amiodarone [PDF]

open access: yes, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo   +5 more
core   +1 more source

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