Bisphosphonat kezelés hatása a csontok fibrosus dysplasiájára = The effect of bisphosphonate treatment on the fibrous dysplasia [PDF]
, 2008 A SE Ortopédiai Klinikán külföldi tapasztalatok alapján 2002-től 6 beteget kezeltünk 3 éves időtartamig iv. és per os, majd 2004 és 2006 között további 11 beteget 1 éves időtartamig per os adott BP-tal.
Kiss, János +2 more
core
Difficult diagnosis and genetic analysis of fibrodysplasia ossificans progressiva: a case report
BMC Medical Genetics, 2018 Background Fibrodysplasia ossificans progressiva (FOP), an ultra-rare and disabling genetic disorder of skeletal malformations and progressive heterotopic ossification, is caused by heterozygous activating mutations in activin A receptor, type I/activin ...
Shengjie Tian, Jianhua Zhu, Yaogang Lu
doaj +1 more source
TGF-beta signaling proteins and the Protein Ontology [PDF]
, 2009 The Protein Ontology (PRO) is designed as a formal and principled Open Biomedical Ontologies (OBO) Foundry ontology for proteins. The components of PRO extend from a classification of proteins on the basis of evolutionary relationships at the ...
Cathy, Wu +7 more
core
Momelotinib: Mechanism of action, clinical, and translational science
Clinical and Translational ScienceMyelofibrosis is a chronic myeloproliferative disorder characterized by bone marrow fibrosis, splenomegaly, anemia, and constitutional symptoms, with a median survival of ≈6 years from diagnosis.
Georgios Vlasakakis +8 more
doaj +1 more source
Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]
, 2010 Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Dimitris Anastassiou +3 more
core +1 more source
Fibrodysplasia Ossificans Progressiva: Clinical and Genetic Aspects [PDF]
, 2011 Robert J Pignolo +2 more
core +1 more source
The HIF-1α and mTOR Pathways Amplify Heterotopic Ossification
BiomoleculesFibrodysplasia ossificans progressiva (FOP; MIM# 135100) is an ultra-rare congenital disorder caused by gain-of-function point mutations in the Activin receptor A type I (ACVR1, also known as ALK2) gene.
Haitao Wang +2 more
doaj +1 more source
The Mütter Museum of the College of Physicians of Philadelphia: An introduction to its history and resources for the teaching of human developmental biology [PDF]
, 2008 Grunwald, Gerald B.
core +4 more sources
Histone Variant H3.3: A versatile H3 variant in health and in disease [PDF]
, 2016 core +1 more source