Results 111 to 120 of about 4,120 (178)

A new BMP type 1 receptor kinase inhibitor for safe and efficient oral treatment to prevent genetically induced heterotopic ossification in mice. [PDF]

Bone
Yang J, Pan H, Sekimata K, Hwang C, Kulkarni A, Thomas H, Lindenau J, Duford T, Ueharu H, Tanaka A, Sakai N, Shirouzu M, Hashizume Y, Levi B, Koyama H, Mishina Y.   +15 more
europepmc   +1 more source

Theoretical-Experimental Analysis to Elucidate the Mechanism of Action of Novel Anabolic Agents. [PDF]

Molecules
Quiroga I, Cardenas-Garcia M, Hernández-Linares MG, Guerrero-Luna G, Flores-Manuel F.   +4 more
europepmc   +1 more source

Intermittent and Short-Term Empirical Ruxolitinib Regimen for Steroid-Refractory Flareups of Fibrodysplasia Ossificans Progressiva. [PDF]

Pharmacol Res Perspect
Chen RL, Yang TH, Wang YH, Shaw JJ, Chen LY.   +4 more
europepmc   +1 more source

Inhibition of astrocyte BMP signaling alleviates neuroinflammation in experimental models of Parkinson's disease. [PDF]

Cell Death Discov
Li Y, Li Y, Hao J, Wang W, Su Z, Tian X, Wang H, Liu Q, Gao J, Geng D, Wang L.   +10 more
europepmc   +1 more source

An inducible knock-in mouse model of fibrodysplasia ossificans progressiva shows spontaneous formation of heterotopic ossification. [PDF]

JBMR Plus
Chakkalakal SA, Großmann NZ, Mejías Rivera L, Roberts DW, Pacifici M, Mourkioti F, Shore EM.   +6 more
europepmc   +1 more source

ACVR1 mutations—a key piece in paediatric diffuse glioma [PDF]

Nature Reviews Clinical Oncology, 2014
openaire   +1 more source

Single-cell and bulk transcriptomic analyses uncover immune subtypes associated with programmed cell death features in intrahepatic cholangiocarcinoma. [PDF]

Sci Rep
Zhang T, Dou D, Liu Q, Xu D, Wang T, Liu R, Lu D, Zhao X, Wang S, Zhang H.   +9 more
europepmc   +1 more source

Advancements in mechanisms and drug treatments for fibrodysplasia ossificans progressiva. [PDF]

J Zhejiang Univ Sci B
Zhou Y, Shi C, Sun H.
europepmc   +1 more source

GNAS/PKA signaling promotes aberrant osteochondral differentiation of Gli1⁺ tendon sheath progenitors. [PDF]

EMBO J
Chen L, Peng C, Chai L, Zhang R, Zhu C, Wang H, Cheng Q, Yan Y, Shen C, Zheng H, Yang J, Fan H, Kan C.   +12 more
europepmc   +1 more source

PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification. [PDF]

Elife
Valer JA, Deber A, Wits M, Pimenta-Lope C, Goumans MJ, Rosa JL, Sánchez-Duffhues G, Ventura F.   +7 more
europepmc   +1 more source