Purification Of Acvr1 For Co_Crystallisation With Ldn_193189 And Other Compounds
, 2018 Purification protocol for ACVR1 and crystallisation with different compounds.
Adamson, Roslin +3 more
openaire +1 more source
The role of small RNAs in Paget's associated osteosarcoma [PDF]
, 2018 Small RNAs (sRNAs) are a class of non-coding RNA molecules that arekey regulators of gene expression. SRNAs are also specific biomarkersdue to their dysregulation in disease.
Green, Darrell +2 more
core +1 more source
Case Reports in Genetics, 2013 Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare genetic disease that is characterised by congenital malformations of the great toes and progressive heterotopic ossification (HO) in specific anatomical areas. This disease is caused by
Rafael Herrera-Esparza +7 more
doaj +1 more source
Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis
Disease Models & Mechanisms, 2012 Fibrodysplasia ossificans progressiva (FOP; MIM #135100) is a debilitating genetic disorder of connective tissue metamorphosis. It is characterized by malformation of the great (big) toes during embryonic skeletal development and by progressive ...
Frederick S. Kaplan +2 more
doaj +1 more source
TGF-beta signaling proteins and the Protein Ontology [PDF]
, 2009 The Protein Ontology (PRO) is designed as a formal and principled Open Biomedical Ontologies (OBO) Foundry ontology for proteins. The components of PRO extend from a classification of proteins on the basis of evolutionary relationships at the ...
Cathy, Wu +7 more
core
Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]
, 2010 Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Dimitris Anastassiou +3 more
core +1 more source
Momelotinib: Mechanism of action, clinical, and translational science
Clinical and Translational ScienceMyelofibrosis is a chronic myeloproliferative disorder characterized by bone marrow fibrosis, splenomegaly, anemia, and constitutional symptoms, with a median survival of ≈6 years from diagnosis.
Georgios Vlasakakis +8 more
doaj +1 more source
Bisphosphonat kezelés hatása a csontok fibrosus dysplasiájára = The effect of bisphosphonate treatment on the fibrous dysplasia [PDF]
, 2008 A SE Ortopédiai Klinikán külföldi tapasztalatok alapján 2002-től 6 beteget kezeltünk 3 éves időtartamig iv. és per os, majd 2004 és 2006 között további 11 beteget 1 éves időtartamig per os adott BP-tal.
Kiss, János +2 more
core
Sequencing of ACVR1/ALK2 in patient derived DIPG cell lines
, 2019 Report outlining how genomic DNA was extracted from patient derived diffuse intrinsic pontine glioma cell lines*, PCR was used to amplify commonly mutated exons of ACVR1, and the regions Sanger sequenced.
Brown, Elizabeth, Bullock, Alex
openaire +1 more source
Purification Of Acvr1 Alone And Tgfbr1 (Alk5) Complexed With Fkbp12
, 2018 Purifications of ALK2 and ALK5 (the latter in complex with FKBP12) and crystal ...
Adamson, Roslin +3 more
openaire +1 more source