Results 121 to 130 of about 5,020 (198)

Rare variant analysis of whole genome sequenced juvenile idiopathic arthritis multiplex pedigrees identifies rare variants in NOD2 and ACVR1. [PDF]

G3 (Bethesda)
Avery CN, Hernandez EJ, Kazuko SG, Bohnsack JF, Sudman M, Prahalad S, Radmall K, Hersh AO, Letsou A, Jorde LB.   +9 more
europepmc   +1 more source

The diagnostic journey of fibrodysplasia ossificans progressiva: evidence from a national cohort of 114 patients. [PDF]

Front Endocrinol (Lausanne)
Cui L, Ouyang Q, Guo J, Cai W, Pang Q, Chi Y, Jiajue R, Li X, Liu W, Jiang Y, Wang O, Li M, Xing X, Xu Q, Xia W.   +14 more
europepmc   +1 more source

BCX9250 is a potent small-molecule inhibitor of Activin A Receptor Type 1 (ACVR1/ALK2) for fibrodysplasia ossificans progressiva. [PDF]

JBMR Plus
Wang H, Toutounchi S, Pignolo RJ, Cheng X, Parker CD, Liu Q, Muppa S, Kellogg-Yelder D, Polach KJ, Kotian PL, Babu YS, Chen X.   +11 more
europepmc   +1 more source

A pontine-specific niche supports de novo gliomagenesis. [PDF]

Cell Rep
Pathak A, Wells GB, Bankaitis VA, Xie Z.
europepmc   +1 more source

Hepcidin as a Molecular Hub of Iron Homeostasis: From BMP-SMAD Signaling to Therapeutic Modulation. [PDF]

Biomolecules
Duminuco A, Costa A, Pilo F, Scarso S, Giallongo C, Giallongo S, Santisi A, Sbriglione A, Santocono L, Caocci G, Palumbo GA.   +10 more
europepmc   +1 more source

Fibrodysplasia ossificans progressiva in children: diagnostic pitfalls and ACVR1 genotype-phenotype spectrum. [PDF]

Eur J Pediatr
Acikgoz NB, Senkalfa B, Celik Ertas B, Ozdemir Uslu Z, Helhel E, Urel Demir G, Alanay Y, Yildiz AE, Utine GE, Ozon ZA, Simsek Kiper PO.   +10 more
europepmc   +1 more source

Single-base 2'OMe-modified LNA and MOE gapmers selectively silence <i>ACVR1</i> ^<i>R206H</i> in fibrodysplasia ossificans progressiva. [PDF]

Mol Ther Nucleic Acids
Anwar S, Hay S, Moriyama H, Mir F, Maruyama R, Yokota T.   +5 more
europepmc   +1 more source

Fibrodysplasia Ossificans Progressiva: Clinicoradiological Insights Into a Rare Case. [PDF]

Cureus
Nanda G, Mohanty B, Mohapatra S, Singh M.   +3 more
europepmc   +1 more source

USP24-dependent STAT2 stabilization mediates physiologic and pathologic bone formation. [PDF]

Cell Death Dis
Kim JM, Yang YS, Xie J, Kang CM, Cho YC, Park KH, Gong F, Sato T, Kim BJ, Gao G, Shim JH.   +10 more
europepmc   +1 more source

Orosomucoid 2 promotes colorectal cancer liver metastasis by suppressing natural killer cell-mediated antitumor immunity by remodeling the serine and one-carbon metabolism pathway. [PDF]

Mol Cancer
Zhou J, He X, Xiang Z, Wang M, Xu W, Wang Y, Chen Y, Zhang T, Wang L, Mao A.   +9 more
europepmc   +1 more source