Results 91 to 100 of about 4,120 (178)

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HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

A closed-loop cell therapy engineered to autonomously secrete activin A inhibitor protects from fibrodysplasia ossificans progressiva

iScience
Summary: Engineered cell therapies present an opportunity for endogenous, site-specific production of therapeutic agents. Fibrodysplasia ossificans progressiva (FOP) is a morbid condition in which patients develop extensive heterotopic bony lesions in ...
Pratik Koirala, Ziyu Chen, Mengfan Wu, David Maridas, Ashley Siegel, Chang Liu, Samerender Hanumantharao, Yuji Mishina, Vicki Rosen, Shailesh Agarwal   +9 more
doaj   +1 more source

ACVR1 Allele-Specific Antisense Oligonucleotides

IPFS: QmNPT5Mzt9mwnFUreNhNsjjm4fECQT9Xjf5MNyAgT5pDMi. TX: 0xc6ffa10bd0cd44e5c98d54fe485efc5d46a4aaf1936f8bec57c4ea97a478c0b9. CC0.
openaire   +1 more source

ACVR1 wt Allele [PDF]

, 2020
openaire   +1 more source

Imatinib Repurposing for ACVR1 Downstream Signaling Inhibition

IPFS: QmQp88cmTnfSNBeTvggvrqUSDn52KZcMXnUUUG6GwoJWNV. TX: 0x5d6e87921cd14d0ed369673eb4b9420a0b8f22cebd7cb561052d47a78accde68. CC0.
openaire   +1 more source

Fibrodysplasia ossificans progressiva in children: diagnostic pitfalls and ACVR1 genotype-phenotype spectrum. [PDF]

Eur J Pediatr
Acikgoz NB, Senkalfa B, Celik Ertas B, Ozdemir Uslu Z, Helhel E, Urel Demir G, Alanay Y, Yildiz AE, Utine GE, Ozon ZA, Simsek Kiper PO.   +10 more
europepmc   +1 more source

Single-base 2'OMe-modified LNA and MOE gapmers selectively silence <i>ACVR1</i> ^<i>R206H</i> in fibrodysplasia ossificans progressiva. [PDF]

Mol Ther Nucleic Acids
Anwar S, Hay S, Moriyama H, Mir F, Maruyama R, Yokota T.   +5 more
europepmc   +1 more source

Orosomucoid 2 promotes colorectal cancer liver metastasis by suppressing natural killer cell-mediated antitumor immunity by remodeling the serine and one-carbon metabolism pathway. [PDF]

Mol Cancer
Zhou J, He X, Xiang Z, Wang M, Xu W, Wang Y, Chen Y, Zhang T, Wang L, Mao A.   +9 more
europepmc   +1 more source

The role of muscle fascia in heterotopic ossification and maintenance of skeletal muscle integrity in fibrodysplasia ossificans progressiva. [PDF]

Bone
Hanson LR, Scalise KL, Esch RM, Nevo L, Goldhamer DJ.   +4 more
europepmc   +1 more source

Lineage tracing of soma-to-primordial germ cell-like conversion in human tumor cell line. [PDF]

iScience
Li J, Zhang F, Xiong J, Liu A, Liu P, Ma Z, Lin HK, Liu C.   +7 more
europepmc   +1 more source