Results 71 to 80 of about 5,020 (198)

TGF‐β/Smad‐Associated Epithelial–Fibroblast Remodeling Underlies Collagen Deposition in Chronic Rhinosinusitis With Nasal Polyps

Immunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is frequently accompanied by epithelial barrier disruption and tissue remodeling. This study aimed to investigate whether epithelial–mesenchymal transition (EMT), fibroblast activation, collagen deposition, and TGF‐β/Smad signaling are coordinated during CRSwNP nasal mucosal ...
Shilong Liu, Peizheng Xie, Hanwei Deng, Zhenhua Zhu   +3 more
wiley   +1 more source

Virus Titration And Test Expression Of Acvr1

, 2018
Test expression of ACVR1 using different virus levels to infect the insect cells. Purification of tests.
Adamson, Roslin, Brennan, Paul, Mateucci, Mizio, Bullock, Alex   +3 more
openaire   +1 more source

Fibrodysplasia ossificans progressiva with minor unilateral hallux anomaly in a sporadic case from Northern Tanzania with the common ACVR1c.617G A mutation

The Pan African Medical Journal, 2015
Fibrodysplasia ossificans progressiva is a rare autosomal dominantly inherited disorder of connective tissue caused by mutations in the gene encoding for ACVR1/ALK2, a bone morphogenetic protein type I receptor.
Mohammed Saleh, Joost Commandeur, Renata Bocciardi, Grace Kinabo, Ben Hamel   +4 more
doaj   +1 more source

The German ONKOPEDIA Guideline for Myelofibrosis in 2025—Recommendations of an MPN Expert Panel of the German Society for Hematology and Oncology (DGHO)

International Journal of Cancer, Volume 159, Issue 7, Page 1633-1641, 1 October 2026.
ABSTRACT The recently published ONKOPEDIA guideline on myelofibrosis, issued under the auspices of the German Society of Hematology and Oncology (DGHO), provides an updated, evidence‐based framework for the diagnosis and management of this rare, chronic myeloproliferative neoplasm.
Martin Griesshammer, Haifa Kathrin Al‐Ali, Gabriela M. Baerlocher, Konstanze Döhner, Steffen Koschmieder, Nicolaus Kröger, Petro E. Petrides, Dominik Wolf, Florian H. Heidel   +8 more
wiley   +1 more source

Data from: Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop

, 2020
Activin A functions in BMP signaling in two ways: it either engages ACVR1B to activate Smad2/3 signaling or binds ACVR1 to form a non-signaling complex (NSC).
Aykul, Senem
core   +1 more source

Integrating novel therapeutic strategies in myeloproliferative neoplasms: Driving disease‐directed progress

British Journal of Haematology, Volume 209, Issue 4, Page 1450-1468, October 2026.
Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo, Maria Georgiou, Donal P. McLornan, Claire N. Harrison   +3 more
wiley   +1 more source

Differentially expressed miRNA Cargo From Boar Seminal Extracellular Vesicles Is Linked With Motility Quality in AI Doses

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT Sperm motility is a key parameter for male selection and is closely linked to male fertility status. miRNAs have been proposed as fertility biomarkers, and their regulatory effects on sperm motility have been previously investigated. In the present study, the miRNA cargo from three different sources, seminal extracellular vesicles, free ...
Adrián Martín‐San Juan, Claudia Cerrato Martín‐Hinojal, Helena Nieto‐Cristóbal, Maria José Martinez‐Alborcia, Eduardo de Mercado, Manuel Álvarez‐Rodríguez   +5 more
wiley   +1 more source

ACVR1 1.25 Å and 2 Å datasets for M4K2117 and M4K2121

, 2018
Autoprocessed .mtz files for ACVR1 bound to M4K2117 and ...
Brennan, Paul (4954291), Mateucci, Mizio (5217614), Bullock, Alex, Bullock, Alex (4954282), Adamson, Roslin, Adamson, Roslin (4977725), Brennan, Paul, Mateucci, Mizio   +7 more
core   +1 more source

Dynamic Remodeling of Oocyte‐Granulosa Cell Communication During Bovine Folliculogenesis Revealed by Transcriptomic Meta‐Analyses

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Bidirectional communication between oocytes and granulosa cells undergoes progressive remodeling during bovine folliculogenesis. Integrative transcriptomic analysis identified stage‐specific ligand‐receptor signaling networks coordinating structural, metabolic, and developmental processes.
Noemi Monferini, Ludovica Donadini, Pritha Dey, Federica Franciosi, Valentina Lodde, Maria Belen Rabaglino, Alberto Maria Luciano   +6 more
wiley   +1 more source

Clinical Aspects and Current Therapeutic Approaches for FOP

Biomedicines, 2020
Fibrodysplasia ossificans progressiva (FOP) is an extremely rare heritable disorder of connective tissues characterized by progressive heterotopic ossification in various skeletal sites.
Hiroshi Kitoh
doaj   +1 more source