Results 171 to 180 of about 96,079 (210)
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Solution structural features of N -acyl homoserine lactones
Tetrahedron Letters, 2015Here we demonstrate that in interbacterial quorum signal moderators, N-acylhomoserine lactones (AHLs), the stabilization of bioactive pharmacophore lactone against lysis is through the e(-) withdrawing N-acyl motif which reduces lactone carbonyl polarization. This lysis is assisted by weak (
Tumminakatti, Shama +4 more
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Modeling the effect of acylated homoserine lactone antagonists in Pseudomonas aeruginosa
Biosystems, 2005Pseudomonas aeruginosa is a gram-negative bacterium that causes serious illnesses, particularly in immunocompromised individuals, often with a fatal outcome. The finding that the acylated homoserine lactone quorum sensing (QS) system controls the production of virulence factors in P.
Magnus G, Fagerlind +5 more
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Self perception in bacteria: quorum sensing with acylated homoserine lactones
Current Opinion in Microbiology, 1998A variety of Gram-negative bacteria produce membrane permeant, acylated homoserine lactone (HL) pheromones that act as cell density cues. Synthesis and response to these factors requires proteins homologous to the Luxl acylhomoserine lactone synthase and the LuxR transcription factor from Vibrio fischeri.
C, Fuqua, E P, Greenberg
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Molecular mechanisms of N‐acyl homoserine lactone signals perception by plants
Cell Biology International, 2021AbstractN‐acyl homoserine lactones (AHLs) belong to the class of bacterial quorum sensing signal molecules involved in distance signal transduction between Gram‐negative bacteria colonizers of the rhizosphere, as well as bacteria and plants. AHLs synchronize the activity of genes from individual cells, allowing the bacterial population to act as a ...
Lidia M. Babenko +2 more
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New temperature-switchable acyl homoserine lactone-regulated expression vector
Applied Microbiology and Biotechnology, 2022Bacterial expression systems play an indispensable role in the biosynthesis of recombinant proteins. Different proteins and the tasks associated with them may require different systems. The purpose of this work is to make an expression vector that allows switching on and off the expression of the target gene during cell incubation.
Sergey V, Bazhenov +5 more
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Acyl-Homoserine Lactone Quorum Sensing: From Evolution to Application
Annual Review of Microbiology, 2013Quorum sensing (QS) is a widespread process in bacteria that employs autoinducing chemical signals to coordinate diverse, often cooperative activities such as bioluminescence, biofilm formation, and exoenzyme secretion. Signaling via acyl-homoserine lactones is the paradigm for QS in Proteobacteria and is particularly well understood in the ...
Martin, Schuster +3 more
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Acyl-Homoserine Lactone Biosynthesis: Structure and Mechanism
2014The first quorum-sensing system to be discovered was the Lux system of Vibrio fischeri, which regulates light production in the light organ of deep sea fish and squid via an acyl-homoserine lactone (AHL) signaling molecule. The LuxI-type AHL synthases catalyze the formation of the AHL from the substrates S-adenosyl-L-methionine (SAM) and acyl-acyl ...
Mair E. A. Churchill, Jake P. Herman
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The role of N-acyl homoserine lactones in maintaining the stability of aerobic granules
Bioresource Technology, 2014In this study, porcine kidney acylase, as N-acyl homoserine lactones (AHLs)-degradation enzyme, was employed for the first time to directly investigate the role of AHLs in the structure stability of aerobic granules. Results clearly showed that inactivation of AHLs by AHLs-acylase could weaken the stability of aerobic granule.
Yaochen, Li +5 more
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Acylated Homoserine Lactone Signaling in Marine Bacterial Systems
2014This chapter reviews the current understanding of acylated homoserine lactone (AHL) signaling in marine bacterial systems outside of the well-described Vibrio fischeriand Vibrio harveyi models. AHL production has far only been documented in proteobacterial groups.
Elisha M. Cicirelli +3 more
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Determination of Acyl Homoserine Lactone and Tetramic Acid Concentrations in Biological Samples
2010Within environmental communities, there is a constant struggle for survival, as nutrients are often limited. In response, bacteria have developed elaborate methods to deal with competitors. One such mechanism is the coordination of behaviors and function via the exchange of small chemical signals in a process known as quorum sensing.
Colin A, Lowery +2 more
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