Results 101 to 110 of about 89,283 (289)
Proteome and Histone-like Acetylation Analysis of Conjugated Linoleic Acid Production by Lactobacillus plantarum p-8 Induced by Linoleic Acid [PDF]
Shipin KexueIn this study, changes in proteome and histone-like acetylation levels of Lactobacillus plantarum p-8 induced by linoleic acid (LA) were explored to investigate the mechanism of conjugated linoleic acid (CLA) production.
LI Ruihua, QIN Yali, DONG Qigeqi, ZHANG Heping, ZHAO Guofen
doaj +1 more source
Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules. [PDF]
, 2019 Covalent post-translational modification (PTM) of proteins with acyl groups of various carbon chain-lengths regulates diverse biological processes ranging from chromatin dynamics to subcellular localization.
Chua, Katrin F +7 more
core +1 more source
The dynamic organization of fungal acetyl-CoA carboxylase [PDF]
, 2016 Acetyl-CoA carboxylases (ACCs) catalyse the committed step in fatty-acid biosynthesis: the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. They are important regulatory hubs for metabolic control and relevant drug targets for the treatment of ...
Hagmann, Anna +4 more
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Advanced Science, EarlyView.In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi +10 more
wiley +1 more source
Biologia Plantarum, 2015 Saussurea involucrata Kar. et Kir. tolerates severe abiotic stresses including cold, and the level of membrane fatty acid desaturation is associated with its cold acclimation.
H. -L. Liu +5 more
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Single muscle fiber proteomics reveals unexpected mitochondrial specialization [PDF]
, 2015 Mammalian skeletal muscles are composed of multinucleated cells termed slow or fast fibers according to their contractile and metabolic properties. Here, we developed a high-sensitivity workflow to characterize the proteome of single fibers.
A. S., Deshmukh +8 more
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CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride Turnover
Advanced Science, EarlyView.This study identifies CIDEC, an lipid droplet (LD)‐fusion associated protein upregulated by CREBH during early regeneration, as a negative regulator of liver regeneration through its unexpected role in sequestering triglyceride (TG) within LDs. CIDEC depletion reduces LD size, mobilizes LD‐stored TG, enhances TG catabolism and free fatty acid (FFA ...
Feng Ouyang +16 more
wiley +1 more source
Elucidating fish oil-induced milk fat depression in dairy sheep: Milk somatic cell transcriptome analysis [PDF]
, 2017 9 páginas, 4 figuras.In this study, RNA sequencing was used to obtain a comprehensive profile of the transcriptomic changes occurring in the mammary gland of lactating sheep suffering from fish oil-induced milk fat depression (FO-MFD).
Arranz, Juan José +5 more
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Advanced Science, EarlyView.Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo +17 more
wiley +1 more source
Template-directed biopolymerization: tape-copying Turing machines
, 2012 DNA, RNA and proteins are among the most important macromolecules in a living cell. These molecules are polymerized by molecular machines. These natural nano-machines polymerize such macromolecules, adding one monomer at a time, using another linear ...
Chowdhury, Debashish, Sharma, Ajeet K.
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