Results 141 to 150 of about 47,958 (242)

Vibrio cholerae can Recycle Fatty Acids Via an Acyl-Acyl Carrier Protein Synthetase. [PDF]

Curr Microbiol
Platt AJ, Ma AT, Beld J.
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Structural and Dynamic Insights into Acyl Carrier Protein upon Metal Binding and Acylation Revealed by NMR Spectroscopy and MD Simulations. [PDF]

Int J Mol Sci
Lee CY, Jang S, Cho H, Jeong MC, Oh Y, Kim Y.   +5 more
europepmc   +1 more source

Malonyl-acyl carrier protein decarboxylase activity promotes fatty acid and cell envelope biosynthesis in Proteobacteria. [PDF]

J Biol Chem, 2021
Whaley SG, Radka CD, Subramanian C, Frank MW, Rock CO.   +4 more
europepmc   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

BMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing, Yuhui Yang, Ziyi Zhao, Kai Lv, Yiran Shao, Zhi Zhang, Dong Ma   +6 more
wiley   +1 more source

Two putative <i>Enterococcus faecalis fabG</i> genes do not encode β-ketoacyl-acyl carrier protein reductases. [PDF]

Microbiology (Reading)
Zou Q, Dong H, Cronan JE.
europepmc   +1 more source

A GX₂GX₃G motif facilitates acyl chain sequestration by Saccharomyces cerevisiae acyl carrier protein. [PDF]

J Biol Chem, 2021
Garima, Prem R, Yadav U, Sundd M.
europepmc   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Coordinated Biosynthesis of Essential Cell Envelope Components: Lipopolysaccharide and Fatty Acids Requires LapD, Acyl Carrier Protein, and Fully Hexaacylated Lipid A. [PDF]

Int J Mol Sci
Jeschke M, Ayyolath A, Maniyeri A, Raina S, Klein G.   +4 more
europepmc   +1 more source

Lipoate protein ligase B primarily recognizes the C₈-phosphopantetheine arm of its donor substrate and weakly binds the acyl carrier protein. [PDF]

J Biol Chem, 2022
Dhembla C, Yadav U, Kundu S, Sundd M.
europepmc   +1 more source