Results 181 to 190 of about 89,834 (290)
Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda +5 more
wiley +1 more source
Switching the strict substrate specificities of the β-ketoacyl-acyl carrier protein synthases, FabH and BioZ. [PDF]
Hang X +7 more
europepmc +1 more source
Intracellular cholesterol transport proteins: roles in health and disease [PDF]
Graham, Annette, Soffientini, Ugo
core +1 more source
C‐Terminal Nucleobase Modification Amplifies Peptide‐Mediated Liposome Fusion
Let's come together right now. Cationic peptides are known to promote aggregation of negatively charged liposomes through electrostatic interaction. The process is reversible: once neutrality is achieved, liposomes disaggregate. Here, we demonstrate that end‐capping peptides with nucleobases turns the process into irreversible fusion.
Laura Morbiato +4 more
wiley +1 more source
Identification, structure determination and analysis of Mycobacterium smegmatis acyl-carrier protein synthase (AcpS) crystallized serendipitously. [PDF]
Bhatia I, Yadav S, Biswal BK.
europepmc +1 more source
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami +2 more
wiley +1 more source
Vibrio cholerae can Recycle Fatty Acids Via an Acyl-Acyl Carrier Protein Synthetase. [PDF]
Platt AJ, Ma AT, Beld J.
europepmc +1 more source
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler +3 more
wiley +1 more source

