Results 191 to 200 of about 89,834 (290)

Design, synthesis, and molecular modeling of novel thiazolopyridine-based inhibitors of enoyl acyl carrier protein reductase (InhA) as anti-<i>Mycobacterium tuberculosis</i> agents. [PDF]

RSC Med Chem
Sabt A, Korycka-Machała M, Kassem AF, Saleh AM, Farag H, Shaldam MA, Thabit MG, Brzostek A, Kuzioła M, Dziadek B, Ibrahim HAA, Lei X, Dziadek J, Abdelrahman MA.   +13 more
europepmc   +1 more source

Malonyl-acyl carrier protein decarboxylase activity promotes fatty acid and cell envelope biosynthesis in Proteobacteria. [PDF]

J Biol Chem, 2021
Whaley SG, Radka CD, Subramanian C, Frank MW, Rock CO.   +4 more
europepmc   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Structural and Dynamic Insights into Acyl Carrier Protein upon Metal Binding and Acylation Revealed by NMR Spectroscopy and MD Simulations. [PDF]

Int J Mol Sci
Lee CY, Jang S, Cho H, Jeong MC, Oh Y, Kim Y.   +5 more
europepmc   +1 more source

Lipoate protein ligase B primarily recognizes the C₈-phosphopantetheine arm of its donor substrate and weakly binds the acyl carrier protein. [PDF]

J Biol Chem, 2022
Dhembla C, Yadav U, Kundu S, Sundd M.
europepmc   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Coordinated Biosynthesis of Essential Cell Envelope Components: Lipopolysaccharide and Fatty Acids Requires LapD, Acyl Carrier Protein, and Fully Hexaacylated Lipid A. [PDF]

Int J Mol Sci
Jeschke M, Ayyolath A, Maniyeri A, Raina S, Klein G.   +4 more
europepmc   +1 more source

A GX₂GX₃G motif facilitates acyl chain sequestration by Saccharomyces cerevisiae acyl carrier protein. [PDF]

J Biol Chem, 2021
Garima, Prem R, Yadav U, Sundd M.
europepmc   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

Snapshots of acyl carrier protein shuttling in human fatty acid synthase. [PDF]

Nature
Schultz K, Costa-Pinheiro P, Gardner L, Pinheiro LV, Ramirez-Solis J, Gardner SM, Wellen KE, Marmorstein R.   +7 more
europepmc   +1 more source