Results 261 to 270 of about 80,359 (315)
ChemBioChem, EarlyView.A putative thrazarine biosynthetic gene cluster is discovered in the genome sequence of Streptomyces coerulescens MH802‐fF5. In vivo and in vitro analyses of ThzN, a hydrazine synthetase with cupin and methionyl‐tRNA synthetase‐like domains encoded in the cluster, showed that it synthesizes a key intermediate of thrazarine by catalyzing condensation ...
Yusuke Shikai +4 more
wiley +1 more source
Synthesis of an acyl-acyl carrier protein synthetase inhibitor to study fatty acid recycling. [PDF]
Sci Rep, 2020 Currie MF +5 more
europepmc +1 more source
Solution Structure of B. subtilis Acyl Carrier Protein [PDF]
, 2001 Guangyi Xu +5 more
openalex +1 more source
ChemBioChem, EarlyView.Production of natural products is tightly regulated, resulting in many silent biosynthetic gene clusters. BarA is a repressor that downregulates production of the virginiamycin antibiotics. The VBs are ligands for BarA that reverse its repression of virginiamycin production.
Kylie G. Castator +3 more
wiley +1 more source
Inhibition of β-Ketoacyl-Acyl Carrier Protein Synthases by Thiolactomycin and Cerulenin [PDF]
, 2001 Allen C. Price +5 more
openalex +1 more source
Oxidant‐Free Amidation of Aldehydes Enabled by Electrophotocatalysis
Chemistry – A European Journal, EarlyView.An electrophotocatalytic method for C(sp2)–N bond formation via radical‐polar crossover (RPC)‐HAT catalysis is presented. The mild operating conditions enable functionalization of a wide range of compounds, with electricity as the sole oxidant. Abstract Electrophotocatalysis (EPC) is emerging as a powerful tool in organic synthesis, offering unique ...
Dimitris I. Ioannou +4 more
wiley +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.This graphical abstract illustrates the steps carried out in the laboratory study, including saponin modification and characterization, surface tension, interfacial tension, contact angle, adsorption, and surfactant injection tests. Abstract In this study, three forms of saponin surfactants extracted from the Camellia sinensis plant (CS1, CS2, and CS3)
Iman Nowrouzi +2 more
wiley +1 more source
NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES
ChemMedChem, Accepted Article.Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti +4 more
wiley +1 more source