Results 291 to 300 of about 154,675 (336)
Reprogramming acyl carrier protein interactions of an Acyl-CoA promiscuous trans-acyltransferase.
Zhixia Ye+3 more
semanticscholar +1 more source
Highly water‐soluble Npy‐sulfenate functions as an efficient oxidizing agent for the formation of disulfide bonds in thiol‐containing peptides. The Npy‐sulfenate can be used to form a disulfide bond with a thiol‐containing peptide produced by thiol‐additive‐free NCL, thereby facilitating the one‐pot synthesis of adrenomedullin.
Akihiro Taguchi+8 more
wiley +1 more source
Trapping the dynamic acyl carrier protein in fatty acid biosynthesis
C. Nguyen+13 more
semanticscholar +1 more source
The thiol functionality on the methyl group of a threonine derivative [Thr(SH)] facilitates O‐acylation of the Thr hydroxy group with a thioester. We previously showed that a Thr(SH)‐incorporated peptide thioester can be converted to the corresponding Thr‐containing cyclic depsipeptide through intramolecular thioester exchange (S−S acyl transfer) and ...
Daiki Sato+4 more
wiley +1 more source
Colorimetric Assay Reports on Acyl Carrier Protein Interactions. [PDF]
Acheampong KK+5 more
europepmc +1 more source
Strategy‐Level Prodrug Synthesis
Organic synthesis uniquely provides opportunities to access molecules that serve defined purposes. Medicinal chemistry illustrates this attribute well with prodrug design, whereby a drug undergoes a late‐stage conversion to a conditionally responsive active medicinal agent (AMA), being a notable example.
Paul Geaneotes, Paul Floreancig
wiley +1 more source
PEGylation of the WRAP5‐based nanoparticles via acyl hydrazone linkers is achieved to obtain a pH‐sensitive small interfering ribonucleic acid‐targeted delivery. In acidic extracellular conditions (pH 5) occurring during myocardial ischemia‐reperfusion injury, this optimized delivery system is the only one showing efficient silence of the Fas ...
Giulia Di Gregorio+14 more
wiley +1 more source
Characterization of Acyl Carrier Protein-Dependent Glycosyltransferase in Mitomycin C Biosynthesis. [PDF]
Nguyen HP, Yokoyama K.
europepmc +1 more source