Results 291 to 300 of about 154,675 (336)

Reprogramming acyl carrier protein interactions of an Acyl-CoA promiscuous trans-acyltransferase.

open access: yesChemistry and Biology, 2014
Zhixia Ye   +3 more
semanticscholar   +1 more source

Development of Water‐Soluble 3‐Nitro‐2‐Pyridinesulfenate for Disulfide Bond Formation of Peptide Under Aqueous Conditions

open access: yesChemistry – A European Journal, EarlyView.
Highly water‐soluble Npy‐sulfenate functions as an efficient oxidizing agent for the formation of disulfide bonds in thiol‐containing peptides. The Npy‐sulfenate can be used to form a disulfide bond with a thiol‐containing peptide produced by thiol‐additive‐free NCL, thereby facilitating the one‐pot synthesis of adrenomedullin.
Akihiro Taguchi   +8 more
wiley   +1 more source

Trapping the dynamic acyl carrier protein in fatty acid biosynthesis

open access: yesNature, 2013
C. Nguyen   +13 more
semanticscholar   +1 more source

Late‐stage Intermolecular O‐Peptidylation Protocol Enabled by Sequential Acyl Transfer on Thiol‐incorporated Threonine Followed by Desulfurization

open access: yesChemistry – A European Journal, Accepted Article.
The thiol functionality on the methyl group of a threonine derivative [Thr(SH)] facilitates O‐acylation of the Thr hydroxy group with a thioester. We previously showed that a Thr(SH)‐incorporated peptide thioester can be converted to the corresponding Thr‐containing cyclic depsipeptide through intramolecular thioester exchange (S−S acyl transfer) and ...
Daiki Sato   +4 more
wiley   +1 more source

Colorimetric Assay Reports on Acyl Carrier Protein Interactions. [PDF]

open access: yesSci Rep, 2019
Acheampong KK   +5 more
europepmc   +1 more source

An endogenous proteinacious inhibitor in porcine liver for S-adenosyl-l-methionine dependent methylation reactions: identification as oligosaccharide-linked acyl carrier protein

open access: bronze, 2000
Dong Wan Seo   +7 more
openalex   +1 more source

Strategy‐Level Prodrug Synthesis

open access: yesChemistry – A European Journal, Accepted Article.
Organic synthesis uniquely provides opportunities to access molecules that serve defined purposes. Medicinal chemistry illustrates this attribute well with prodrug design, whereby a drug undergoes a late‐stage conversion to a conditionally responsive active medicinal agent (AMA), being a notable example.
Paul Geaneotes, Paul Floreancig
wiley   +1 more source

Enhancing WRAP‐Based Nanoparticles for Small Interfering Ribonucleic Acid Delivery in pH‐Sensitive Environments

open access: yesChemMedChem, EarlyView.
PEGylation of the WRAP5‐based nanoparticles via acyl hydrazone linkers is achieved to obtain a pH‐sensitive small interfering ribonucleic acid‐targeted delivery. In acidic extracellular conditions (pH 5) occurring during myocardial ischemia‐reperfusion injury, this optimized delivery system is the only one showing efficient silence of the Fas ...
Giulia Di Gregorio   +14 more
wiley   +1 more source

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