Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals
Cell Proliferation, EarlyView.One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye +6 more
wiley +1 more source
Journal of Lipid Research, 2012 Thioesterase superfamily member 1 (Them1; synonyms acyl-CoA thioesterase 11 and StarD14) is highly expressed in brown adipose tissue and limits energy expenditure in mice. Them1 is a putative fatty acyl-CoA thioesterase that comprises tandem hot dog-fold
Shuxin Han, David E. Cohen
doaj
Regulation of glucose uptake by muscle. 10. Effects of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, and of fatty acids, ketone bodies and pyruvate, on the glycerol output and concentrations of free fatty acids, long-chain fatty acyl-coenzyme A, glycerol phosphate and citrate-eyele intermediates in rat heart and diaphragm muscles [PDF]
, 1965 P. B. Garland, P. J. Randle
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Effects of HMG CoA reductase (HMGCR) deficiency on skeletal muscle development
The FEBS Journal, EarlyView.Three skeletal muscle diseases are linked to HMGCR, a key enzyme in cholesterol synthesis. These diseases include a muscular dystrophy associated with pathogenic variants in the HMGCR gene, statin‐associated myopathy, and autoimmune anti‐HMGCR myopathy.
Mekala Gunasekaran +20 more
wiley +1 more source
A simple equation to calculate the diameters of biological vesicles [PDF]
arXiv, 2002 The remarkable preference of biomembranes, to constitute vesicles of certain discrete sizes is explained by using the following properties of phospholipids that are either well understood or at least documented. A. By hexagonal close-packing their fatty acyl chains form a triangular lattice. Their molecules: B.
arxiv
Acyl-coenzyme A binding protein MoAcb1 regulates conidiation and pathogenicity in Magnaporthe oryzae. [PDF]
Front Microbiol, 2023 Cao N +6 more
europepmc +1 more source
The molecular mechanisms of defensive‐grade organic acid biosynthesis in ground beetles
Insect Molecular Biology, EarlyView.Formic acid and methacrylic acid are the primary defensive chemicals in the pygidial gland secretions of Platynus angustatus and Pterostichus moestus, respectively. Comparative transcriptomics suggests the folate cycle and valine catabolism may be involved in the biosynthesis of formic acid and methacrylic acid, respectively.
Adam M. Rork +3 more
wiley +1 more source
Journal of Lipid Research, 1991 Rabbit and human tissues contain substantial amounts of an unusual lipid, a fatty acid ester of a pentacyclic triterpene, that is a potent in vitro inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT). A possible origin of the triterpene ester is via
I Tabas +6 more
doaj
Parameters of cholesterol metabolism in the human hepatoma cell line, Hep-G2.
Journal of Lipid Research, 1988 The human hepatoma cell line Hep-G2 has been shown to express the major enzymes of intra- and extracellular cholesterol metabolism. These include lecithin:cholesterol acyltransferase, acyl coenzyme A:cholesterol acyltransferase, 3-hydroxy-3 ...
S K Erickson, P E Fielding
doaj
Purification and Properties of Long‐Chain Acyl‐Coenzyme‐A Synthetase from Rat Liver [PDF]
, 1979 Takao Tanaka +3 more
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