Results 41 to 50 of about 27,755 (188)

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu   +4 more
wiley   +1 more source

Nickel‐Copper‐Catalyzed Hydroacylation of Vinylarenes with Acyl Fluorides and Hydrosilanes [PDF]

open access: yesChemistry – A European Journal, 2019
AbstractThe hydroacylation of vinylarenes with acyl fluorides and hydrosilanes was enabled by a synergistic bimetallic Ni/Cu‐catalytic system, giving access to the corresponding branched ketone products. The reaction takes place under mild conditions at 25–80 °C and tolerates base‐sensitive functional groups such as methoxycarbonyl and acetoxy groups.
Yusuke Ueda   +2 more
openaire   +3 more sources

Characteristics, properties and limitations of per‐ or polyfluoroalkyl substances (PFASs) and fluoropolymers

open access: yesPolymer International, EarlyView.
An overview and categorization of man‐made per‐ or polyfluoroalkyl substances (PFASs) including low‐molar‐mass and high‐molar‐mass fluorochemicals, and their international regulations is presented. Though certain PFASs are toxic, bioaccumulative and cross the human cellular membranes, others, such as fluoropolymers, are safe, reliable and involved in ...
Bruno Améduri
wiley   +1 more source

Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]

open access: yes, 1991
" An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core   +1 more source

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

open access: yesThe Chemical Record, EarlyView.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source

Synthesis of fluorinated organic compounds using oxygen difluoride [PDF]

open access: yes, 1971
Oxygen difluoride synthesis is a much simpler, higher-yield procedure than reactions originally followed to synthesize various fluorinated organic compounds.
Toy, M. S.
core   +1 more source

The Effect of Highly Hydroxylated Fullerenol C60(OH)36 on Human Erythrocyte Membrane Organization [PDF]

open access: yes, 2015
The mechanism of the interaction of highly hydroxylated fullerenol C60(OH)36 with erythrocyte membranes was studied by electron spin resonance spectroscopy (ESR) of stearic acid derivatives labeled with a nitroxyl radical at C-12 or C-16 and with a ...
Grebowski, Jacek, Krokosz, Anita
core   +3 more sources

Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis. [PDF]

open access: yes, 2020
Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation. Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC ...
Cho, Byong Seung   +19 more
core   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros   +5 more
wiley   +1 more source

A protocol for amide bond formation with electron deficient amines and sterically hindered substrates [PDF]

open access: yes, 2016
A protocol for amide coupling by in situ formation of acyl fluorides and reaction with amines at elevated temperature has been developed and found to be efficient for coupling of sterically hindered substrates and electron deficient amines where standard
Andersen, Rikke   +5 more
core   +1 more source

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