Deoxyfluorination of acyl fluorides to trifluoromethyl compounds by FLUOLEAD®/Olah’s reagent under solvent-free conditions [PDF]
Beilstein Journal of Organic Chemistry, 2020 A new protocol enabling the formation of trifluoromethyl compounds from acyl fluorides has been developed. The combination of FLUOLEAD® and Olah’s reagent in solvent-free conditions at 70 °C initiated the significant deoxyfluorination of the acyl ...
Yumeng Liang +2 more
exaly +3 more sources
Selective O‐Acylation of Enol Silyl Ethers with Acyl Fluorides Catalyzed by Fluoride Ions Derived from Potassium Fluoride and 18‐Crown‐6 [PDF]
ChemistryOpenThe fluoride ion‐catalyzed selective O‐acylation of enol silyl ethers with acyl fluorides using KF and 18‐Crown‐6 is described herein. This catalytic system facilitated the practical and facile reaction of a variety of enol silyl ethers derived from ...
Prof. Dr. Norio Sakai +6 more
doaj +4 more sources
Nickel-Catalyzed Decarbonylative Stannylation of Acyl Fluorides under Ligand-Free Conditions [PDF]
Molecules, 2019 Nickel-catalyzed decarbonylative stannylation of acyl fluorides under ligand-free conditions was disclosed. A variety of aromatic acyl fluorides are capable of reacting with silylstannanes in the presence of cesium fluoride.
Xiu Wang, Yasushi Nishihara
exaly +4 more sources
Copper‐Catalyzed Asymmetric Acylboration of 1,3‐Butadienylboronate with Acyl Fluorides [PDF]
Angewandte Chemie - International Edition, 2023 AbstractWe report herein a Cu‐catalyzed regio‐, diastereo‐ and enantioselective acylboration of 1,3‐butadienylboronate with acyl fluorides. Under the developed conditions, the reactions provide (Z)‐β,γ‐unsaturated ketones bearing an α‐tertiary stereocenter with high Z‐selectivity and excellent enantioselectivities.
Shang Gao, Ming Ｃｈｅｎ
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Direct synthesis of acyl fluorides from carboxylic acids using benzothiazolium reagents [PDF]
Beilstein Journal of Organic Chemistry2-(Trifluoromethylthio)benzothiazolium triflate (BT-SCF3) was used as deoxyfluorinating reagent for the synthesis of versatile acyl fluorides directly from the corresponding carboxylic acids.
Lilian M Maas +2 more
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Rapid and column-free syntheses of acyl fluorides and peptides using ex situ generated thionyl fluoride [PDF]
Chemical Science, 2022 Thionyl fluoride (SOF2) was developed as a rapid acid activation peptide coupling reagent for liquid phase peptide synthesis (LPPS) and solid phase peptide synthesis (SPPS).
Cayo Lee +2 more
openaire +4 more sources
Green Synthesis and Catalysis, 2022 Acyl fluorides are powerful synthons for acylation with wide application in the synthesis of valued compounds, especially peptides. Herein, a practical and catalyst-free method for the synthesis of acyl fluorides from aldehydes via C(sp2)–H fluorination ...
Yatao Lang +2 more
exaly +3 more sources
Photoinduced Cleavage of Alkenyl Fluorides for Nucleophilic Acyl Substitution via In Situ Generated Acyl Fluorides [PDF]
Organic LettersAcyl fluorides are valuable intermediates due to their stability and unique reactivity with amines, enabling selective acyl substitution. We report a mild one-pot method to access amides, esters, and thioesters from alkenyl fluorides. Visible-light photoexcitation of 4-nitrophthalonitrile promotes cleavage of the alkenyl fluoride, forming acyl ...
Emma S. Gogarnoiu +5 more
openaire +3 more sources
Direct Fluoroformylation of the C3‐Position of Indoles with 2,4‐Dinitro(trifluoromethoxy)benzene as Fluorocarbonyl Source [PDF]
ChemistryOpenWe herein report the direct fluoroformylation of indoles and other heteroaromatic cycles. Acyl fluorides are very useful moieties in coupling reactions with or without metal.
Lilian Wisson +5 more
doaj +2 more sources
Production and transport of gaseous 18F-synthons: 18F-acyl fluorides [PDF]
Journal of Fluorine Chemistry, 2015 Fluorine-18 (18F, T 1/2=109.7 min) is a positron-emitting isotope that has found extensive application as a radiolabel for positron emission tomography (PET). Although gaseous 11C-CO2 and 11C-CH4 are practically transported from cyclotron to radiochemistry processes, 18F-fluoride is routinely transported in aqueous solution because it is commonly ...
Huailei Jiang +2 more
openaire +3 more sources