Deoxyfluorination of acyl fluorides to trifluoromethyl compounds by FLUOLEAD®/Olah’s reagent under solvent-free conditions [PDF]
Beilstein Journal of Organic Chemistry, 2020 A new protocol enabling the formation of trifluoromethyl compounds from acyl fluorides has been developed. The combination of FLUOLEAD® and Olah’s reagent in solvent-free conditions at 70 °C initiated the significant deoxyfluorination of the acyl ...
Yumeng Liang +2 more
exaly +3 more sources
Selective O‐Acylation of Enol Silyl Ethers with Acyl Fluorides Catalyzed by Fluoride Ions Derived from Potassium Fluoride and 18‐Crown‐6 [PDF]
ChemistryOpenThe fluoride ion‐catalyzed selective O‐acylation of enol silyl ethers with acyl fluorides using KF and 18‐Crown‐6 is described herein. This catalytic system facilitated the practical and facile reaction of a variety of enol silyl ethers derived from ...
Prof. Dr. Norio Sakai +6 more
doaj +4 more sources
Nickel-Catalyzed Decarbonylative Stannylation of Acyl Fluorides under Ligand-Free Conditions [PDF]
Molecules, 2019 Nickel-catalyzed decarbonylative stannylation of acyl fluorides under ligand-free conditions was disclosed. A variety of aromatic acyl fluorides are capable of reacting with silylstannanes in the presence of cesium fluoride.
Yasushi Nishihara, Xiu Wang
exaly +4 more sources
Copper-Catalyzed Asymmetric Acylboration of 1,3-Butadienylboronate with Acyl Fluorides [PDF]
Angewandte Chemie - International Edition, 2023 AbstractWe report herein a Cu‐catalyzed regio‐, diastereo‐ and enantioselective acylboration of 1,3‐butadienylboronate with acyl fluorides. Under the developed conditions, the reactions provide (Z)‐β,γ‐unsaturated ketones bearing an α‐tertiary stereocenter with high Z‐selectivity and excellent enantioselectivities.
Shang Gao, Ming Chen, Diego Troya
exaly +4 more sources
Direct synthesis of acyl fluorides from carboxylic acids using benzothiazolium reagents [PDF]
Beilstein Journal of Organic Chemistry2-(Trifluoromethylthio)benzothiazolium triflate (BT-SCF3) was used as deoxyfluorinating reagent for the synthesis of versatile acyl fluorides directly from the corresponding carboxylic acids.
Matthew Hopkinson +2 more
exaly +3 more sources
Photoinduced Cleavage of Alkenyl Fluorides for Nucleophilic Acyl Substitution via In Situ Generated Acyl Fluorides. [PDF]
Org LettAcyl fluorides are valuable intermediates due to their stability and unique reactivity with amines, enabling selective acyl substitution. We report a mild, one-pot method to access amides, esters, and thioesters from alkenyl fluorides. Visible-light photoexcitation of 4-nitrophthalonitrile promotes cleavage of the alkenyl fluoride, forming acyl ...
Gogarnoiu ES +5 more
europepmc +3 more sources
Green Synthesis and Catalysis, 2022 Acyl fluorides are powerful synthons for acylation with wide application in the synthesis of valued compounds, especially peptides. Herein, a practical and catalyst-free method for the synthesis of acyl fluorides from aldehydes via C(sp2)–H fluorination ...
Huiying Zeng, Chao-Jun Li, Xiangjun Peng
exaly +3 more sources
Rapid and column-free syntheses of acyl fluorides and peptides using ex situ generated thionyl fluoride. [PDF]
Chem Sci, 2021 Thionyl fluoride (SOF 2 ) was developed as a rapid acid activation peptide coupling reagent for liquid phase peptide synthesis (LPPS) and solid phase peptide synthesis (SPPS).
Lee C, Thomson BJ, Sammis GM.
europepmc +4 more sources
Recycling fluoropolymers to acyl fluorides through shuttle catalysis. [PDF]
Chem SciThe chemical recycling of a small array of fluoropolymers including poly(vinylidene difluoride) is reported.
Farley SES, Fogh AA, Crimmin MR.
europepmc +2 more sources
Direct Fluoroformylation of the C3‐Position of Indoles with 2,4‐Dinitro(trifluoromethoxy)benzene as Fluorocarbonyl Source [PDF]
ChemistryOpenWe herein report the direct fluoroformylation of indoles and other heteroaromatic cycles. Acyl fluorides are very useful moieties in coupling reactions with or without metal.
Lilian Wisson +5 more
doaj +2 more sources