Results 1 to 10 of about 319,348 (202)

Direct synthesis of acyl fluorides from carboxylic acids using benzothiazolium reagents [PDF]

Beilstein Journal of Organic Chemistry
2-(Trifluoromethylthio)benzothiazolium triflate (BT-SCF3) was used as deoxyfluorinating reagent for the synthesis of versatile acyl fluorides directly from the corresponding carboxylic acids.
Lilian M. Maas, Alex Haswell, Rory Hughes, Matthew N. Hopkinson   +3 more
doaj   +12 more sources

Selective O‐Acylation of Enol Silyl Ethers with Acyl Fluorides Catalyzed by Fluoride Ions Derived from Potassium Fluoride and 18‐Crown‐6 [PDF]

ChemistryOpen
The fluoride ion‐catalyzed selective O‐acylation of enol silyl ethers with acyl fluorides using KF and 18‐Crown‐6 is described herein. This catalytic system facilitated the practical and facile reaction of a variety of enol silyl ethers derived from ...
Prof. Dr. Norio Sakai, Kota Watanabe, Haruka Mori, Yuki Maegawa, Ryuki Takeuchi, Dr. Yohei Ogiwara, Dr. Kento Ishida   +6 more
doaj   +5 more sources

Copper-Catalyzed Asymmetric Acylboration of 1,3-Butadienylboronate with Acyl Fluorides. [PDF]

Angew Chem Int Ed Engl, 2023
AbstractWe report herein a Cu‐catalyzed regio‐, diastereo‐ and enantioselective acylboration of 1,3‐butadienylboronate with acyl fluorides. Under the developed conditions, the reactions provide (Z)‐β,γ‐unsaturated ketones bearing an α‐tertiary stereocenter with high Z‐selectivity and excellent enantioselectivities.
Gao S, Liu J, Troya D, Chen M.
europepmc   +6 more sources

Nickel-Catalyzed Decarbonylative Stannylation of Acyl Fluorides under Ligand-Free Conditions [PDF]

Molecules, 2019
Nickel-catalyzed decarbonylative stannylation of acyl fluorides under ligand-free conditions was disclosed. A variety of aromatic acyl fluorides are capable of reacting with silylstannanes in the presence of cesium fluoride.
Xiu Wang, Zhenhua Wang, Li Liu, Yuya Asanuma, Yasushi Nishihara   +4 more
doaj   +7 more sources

In-Flow Generation of Thionyl Fluoride (SOF2) Enables the Rapid and Efficient Synthesis of Acyl Fluorides from Carboxylic Acids [PDF]

JACS Au
Herein, we report an approach for generating thionyl fluoride (SOF2) from the commodity chemicals thionyl chloride (SOCl2) and potassium fluoride (KF).
Daniele Mazzarella, Jelena Stanić, Miguel Bernús, Arad Seyed Mehdi, Cassandra J. Henderson, Omar Boutureira, Timothy Noël   +6 more
doaj   +3 more sources

Photoinduced Cleavage of Alkenyl Fluorides for Nucleophilic Acyl Substitution via In Situ Generated Acyl Fluorides. [PDF]

Org Lett
Acyl fluorides are valuable intermediates due to their stability and unique reactivity with amines, enabling selective acyl substitution. We report a mild, one-pot method to access amides, esters, and thioesters from alkenyl fluorides. Visible-light photoexcitation of 4-nitrophthalonitrile promotes cleavage of the alkenyl fluoride, forming acyl ...
Gogarnoiu ES, Griffin MS, Bansode AH, Paolillo JM, Bergen JM, Parasram M.   +5 more
europepmc   +3 more sources

Rapid and column-free syntheses of acyl fluorides and peptides using ex situ generated thionyl fluoride. [PDF]

Chem Sci, 2021
Thionyl fluoride (SOF2) was developed as a rapid acid activation peptide coupling reagent for liquid phase peptide synthesis (LPPS) and solid phase peptide synthesis (SPPS).
Lee C, Thomson BJ, Sammis GM.
europepmc   +5 more sources

Deoxyfluorination of acyl fluorides to trifluoromethyl compounds by FLUOLEAD®/Olah’s reagent under solvent-free conditions [PDF]

Beilstein Journal of Organic Chemistry, 2020
A new protocol enabling the formation of trifluoromethyl compounds from acyl fluorides has been developed. The combination of FLUOLEAD® and Olah’s reagent in solvent-free conditions at 70 °C initiated the significant deoxyfluorination of the acyl ...
Yumeng Liang, Akihito Taya, Zhengyu Zhao, Norimichi Saito, Norio Shibata   +4 more
doaj   +2 more sources

Direct Synthesis of Various Thioesters from Acyl Fluorides and Thiosilanes through the Assistance of a Si-F Bond Formation. [PDF]

J Org Chem
Herein it is described that the coupling reactions of aromatic and aliphatic acyl fluorides with phenyl trimethylsilyl sulfide proceeded smoothly under neat conditions to produce thioester derivatives. The addition of a catalytic amount of typical bases,
Takeuchi R, Ishida K, Sakai N.
europepmc   +2 more sources

Chemoselective Cu-catalyzed acylsilylation of vinyl arenes using silylboronates and acyl fluorides. [PDF]

Chem Sci
We report the chemoselective copper-catalyzed acylsilylation of vinyl arenes using bench-stable silylboronates and acyl fluorides, which enables efficient access to β-silyl ketones under mild conditions.
Zhao Z, Zhou J, Ochiai S, Ikawa S, Shibata N.   +4 more
europepmc   +2 more sources