Results 41 to 50 of about 319,348 (202)
Preparation and Use of a General Solid-Phase Intermediate to Biomimetic Scaffolds and Peptide Condensations [PDF]
, 2018 The Distributed Drug Discovery (D3) program develops simple, powerful, and reproducible procedures to enable the distributed synthesis of large numbers of potential drugs for neglected diseases.
Martynow, Jacek G. +3 more
core +2 more sources
Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application
European Journal of Organic Chemistry, EarlyView.Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley +1 more source
Isolation, X-ray Structures, and Electronic Spectra of Reactive Intermediates in Friedel−Crafts Acylations [PDF]
, 2005 Reactive intermediates in the Friedel−Crafts acylation of aromatic donors are scrutinized upon their successful isolation and X-ray crystallography at very low temperatures.
Davlieva, M. G. +3 more
core +1 more source
European Journal of Organic Chemistry, EarlyView.1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer +6 more
wiley +1 more source
Process for preparing perfluorotriazine elastomers and precursors thereof [PDF]
, 1984 Perfluoroether triazine elastomers having improved properties and utility in seals, gaskets, sealing components and the like are prepared from oligomeric imidoylamidines that have, in turn, been prepared by the process of (1) reacting a ...
Chen, T. S., Cheng, C. H., Rosser, R. W.
core +1 more source
International Journal of Chemical Kinetics, EarlyView.ABSTRACT The atmospheric chemistry of 1,4‐difluorobutane (CFH2CH2CH2CFH2) was investigated through a kinetic and mechanistic study of the reaction with chlorine (Cl) atoms and hydroxyl (OH) radicals. Using Fourier transform infrared (FTIR) spectroscopy and relative rate methods, the rate constants (k) for the reactions were determined at 298 ± 2 K as k(
Ellen R. Kjaergaard +4 more
wiley +1 more source
Synthesis of a new class of highly fluorinated aliphatic diisocyanates [PDF]
, 1971 Synthesis is basis for preparation of polyurethanes that are compatible with liquid oxygen.
Warner, D. A.
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Non‐small cell lung cancer (NSCLC) is the most common type of lung cancer, with a 5‐year survival rate of less than 20% and a high risk of recurrence despite advances in treatment. This study aimed to identify new therapeutic targets to increase the effectiveness of NSCLC treatments.
Rui‐Shi Wei +5 more
wiley +1 more source
Anion receptor chemistry: highlights from 2011 and 2012
, 2013 This review covers advances in anion complexation in the years 2011 and 2012. The review covers both organic and inorganic systems and also highlights the applications to which anion receptors can be applied such as self-assembly and molecular ...
Busschaert, Nathalie +4 more
core +1 more source
Fluorination methods in drug discovery [PDF]
, 2016 Fluorination reactions of medicinal and biologically-active compounds will be discussed. Late stage fluorination strategies of medicinal targets have recently attracted considerable attention on account of the influence that the fluorine atom can impart ...
Bonesi, Sergio Mauricio +2 more
core +1 more source