Green Synthesis and Catalysis, 2022 Acyl fluorides are powerful synthons for acylation with wide application in the synthesis of valued compounds, especially peptides. Herein, a practical and catalyst-free method for the synthesis of acyl fluorides from aldehydes via C(sp2)–H fluorination ...
Yatao Lang +5 more
doaj +4 more sources
Palladium-Catalyzed Decarbonylative Alkylation of Acyl Fluorides [PDF]
Organic Letters, 2020 Palladium-catalyzed decarbonylative alkylation reactions of acyl fluorides have been developed using alkylboranes having β-hydrogens. A wide range of functional groups were well tolerated, even at the high temperature required for decarbonylation. This protocol provides a diverse C(sp2)-C(sp3) bond formation via a highly efficient decarbonylative ...
Liyan Fu +3 more
openaire +4 more sources
Direct Fluoroformylation of the C3‐Position of Indoles with 2,4‐Dinitro(trifluoromethoxy)benzene as Fluorocarbonyl Source [PDF]
ChemistryOpenWe herein report the direct fluoroformylation of indoles and other heteroaromatic cycles. Acyl fluorides are very useful moieties in coupling reactions with or without metal.
Lilian Wisson +5 more
doaj +2 more sources
Production and Transport of Gaseous 18F-Synthons: 18F-Acyl Fluorides. [PDF]
J Fluor Chem, 2015 Fluorine-18 (18F, T 1/2=109.7 min) is a positron-emitting isotope that has found extensive application as a radiolabel for positron emission tomography (PET). Although gaseous 11C-CO2 and 11C-CH4 are practically transported from cyclotron to radiochemistry processes, 18F-fluoride is routinely transported in aqueous solution because it is commonly ...
Jiang H, DiMagno SG, DeGrado TR.
europepmc +4 more sources
Rapid peptide synthesis using a methylimidazolium sulfinyl fluoride salt [PDF]
Communications ChemistryPeptide couplings have been a subject of investigation for over a century, with modern research seeking to discover new methodologies that minimize purification steps, minimize reagent expense, and/or decrease reaction times.
Joey Lai +4 more
doaj +2 more sources
Enantioselective Acylation of Silyl Ketene Acetals through Fluoride Anion-Binding Catalysis [PDF]
Journal of the American Chemical Society, 2011 A highly-enantioselective acylation of silyl ketene acetals with acyl fluorides has been developed to generate useful \(\alpha\), \(\alpha\)-disubstituted butyrolactone products.
Birrell, James Andrew +2 more
core +5 more sources
Making Acyl Fluorides by Synergistic Palladium/Phosphine-Catalyzed Fluorocarbonylation
Synfacts, 2023 Chromium-Catalysed Cross ...
A. J . LI N D MA N +6 more
openaire +2 more sources
General alkyl fluoride functionalization via short-lived carbocation-organozincate ion pairs [PDF]
Nature CommunicationsFluorinated organic compounds are frequently used across the chemical and life sciences. Although a large, structurally diverse pool of alkyl fluorides is nowadays available, synthetic applications trail behind the widely accepted utility of other ...
D. Lucas Kane +4 more
doaj +2 more sources
Three-Component Coupling of Acyl Fluorides, Silyl Enol Ethers, and Alkynes by P(III)/P(V) Catalysis.
Journal of the American Chemical Society, 2021 We report herein on the phosphine-catalyzed hydrovinylation reaction by three-component coupling of acyl fluorides, silyl enol ethers, and alkynoates.
Hayato Fujimoto +3 more
semanticscholar +3 more sources
Nickel‐Copper‐Catalyzed Hydroacylation of Vinylarenes with Acyl Fluorides and Hydrosilanes [PDF]
Chemistry – A European Journal, 2019 AbstractThe hydroacylation of vinylarenes with acyl fluorides and hydrosilanes was enabled by a synergistic bimetallic Ni/Cu‐catalytic system, giving access to the corresponding branched ketone products. The reaction takes place under mild conditions at 25–80 °C and tolerates base‐sensitive functional groups such as methoxycarbonyl and acetoxy groups.
Yusuke Ueda +2 more
openaire +5 more sources