In-Flow Generation of Thionyl Fluoride (SOF2) Enables the Rapid and Efficient Synthesis of Acyl Fluorides from Carboxylic Acids [PDF]
JACS AuHerein, we report an approach for generating thionyl fluoride (SOF2) from the commodity chemicals thionyl chloride (SOCl2) and potassium fluoride (KF).
Daniele Mazzarella +6 more
doaj +5 more sources
Nickel-Copper-Catalyzed Hydroacylation of Vinylarenes with Acyl Fluorides and Hydrosilanes [PDF]
Chemistry - A European Journal, 2019 AbstractThe hydroacylation of vinylarenes with acyl fluorides and hydrosilanes was enabled by a synergistic bimetallic Ni/Cu‐catalytic system, giving access to the corresponding branched ketone products. The reaction takes place under mild conditions at 25–80 °C and tolerates base‐sensitive functional groups such as methoxycarbonyl and acetoxy groups.
Tomohiro Iwai, Masaya Sawamura
exaly +6 more sources
Palladium-Catalyzed Decarbonylative Alkylation of Acyl Fluorides [PDF]
Organic Letters, 2020 Palladium-catalyzed decarbonylative alkylation reactions of acyl fluorides have been developed using alkylboranes having β-hydrogens. A wide range of functional groups were well tolerated, even at the high temperature required for decarbonylation. This protocol provides a diverse C(sp2)-C(sp3) bond formation via a highly efficient decarbonylative ...
Liyan Fu +3 more
core +7 more sources
Production and Transport of Gaseous 18F-Synthons: 18F-Acyl Fluorides. [PDF]
J Fluor Chem, 2015 Fluorine-18 (18F, T 1/2=109.7 min) is a positron-emitting isotope that has found extensive application as a radiolabel for positron emission tomography (PET). Although gaseous 11C-CO2 and 11C-CH4 are practically transported from cyclotron to radiochemistry processes, 18F-fluoride is routinely transported in aqueous solution because it is commonly ...
Jiang H, DiMagno SG, DeGrado TR.
europepmc +4 more sources
Rapid peptide synthesis using a methylimidazolium sulfinyl fluoride salt [PDF]
Communications ChemistryPeptide couplings have been a subject of investigation for over a century, with modern research seeking to discover new methodologies that minimize purification steps, minimize reagent expense, and/or decrease reaction times.
Joey Lai +4 more
doaj +2 more sources
Photochemical synthesis of acyl fluorides using copper-catalyzed fluorocarbonylation of alkyl iodides [PDF]
, 2023 Acyl fluorides are important reagents in organic synthesis due to their unique balance between reactivity and stability. Here, we report a copper-catalyzed carbonylative coupling strategy to synthesize acyl fluorides under photoirradiation. Various alkyl
Neal, Mankad, Pinku, Tung
core +1 more source
Nickel-Catalyzed Decarbonylative Thioetherification of Acyl Fluorides via C–F Bond Activation [PDF]
, 2021 Nickel-catalyzed decarbonylative thioetherification of acyl fluorides has been developed. This transformation allows an array of acyl fluorides to react with thiophenols. A wide range of functional groups are well tolerated and the corresponding sulfides
Chen, Qiang +2 more
core +2 more sources
, 2023 Acyl fluorides are versatile reagents in organic synthesis. However, there is no precedent to employ acyl fluorides as acyl radical precursors. We herein report an N-heterocyclic nitrenium iodide salt-catalyzed photoreduction of acyl fluorides to produce
Xiang-Yu Chen (2226904) +5 more
core +1 more source
Use of Acid Fluorides Increases the Scope of the Reductive Acylation of Esters [PDF]
Organic Letters, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Yongda, Zhang, Tomislav, Rovis
openaire +2 more sources
Deoxyfluorination of Carboxylic Acids with CpFluor: Access to Acyl Fluorides and Amides
Organic Letters, 2021 3,3-Difluoro-1,2-diphenylcyclopropene (CpFluor), a bench-stable fluorination reagent, has been developed in the deoxyfluorination of carboxylic acids to afford various acyl fluorides. This all-carbon-based fluorination reagent enabled the efficient transformation of (hetero)aryl, alkyl, alkenyl, and alkynyl carboxylic acids to the corresponding acyl ...
Xiu Wang +4 more
openaire +3 more sources