Results 111 to 120 of about 20,316 (189)
Carnitine-Acylcarnitine Translocase Deficiency [PDF]
William L. Nyhan +3 more
+5 more sources
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
A Multi‐Organ Atlas Links Gut Microbial Metabolites to Systemic Redox Changes in Aging Mice
A gut‐derived metabolic signature drives systemic aging phenotypes. Integrated multi‐omics profiling of young versus aged mice identifies a conserved aging signature characterized by the depletion of protective lysophosphatidylcholines (LPC 22:0) and the concurrent accumulation of pro‐oxidative microbial catabolites (TMAO, IAA).
Sanaullah Sajid +6 more
wiley +1 more source
Abstract Background The storage of red blood cells (RBCs) is essential for transfusion but leads to storage lesions that compromise RBC quality and increase the risk of transfusion‐related adverse effects, including allergic transfusion reactions (ATRs). Understanding storage‐induced metabolic change is crucial for enhancing transfusion safety.
Gürkan Bal +5 more
wiley +1 more source
An allostatic load domain‐specific metabolic profile in young adults: The African‐PREDICT study
Abstract figure legend An allostatic load domain‐specific metabolic profile in young adults: The African‐PREDICT study Abstract Allostatic load scores (ALSs) quantify the cumulative physiological burden of sustained stress across neuro‐endocrine, metabolic, cardiovascular and inflammatory domains; however ALS is heterogeneous in nature.
Nevah Joubert +4 more
wiley +1 more source
Quantification of acylcarnitines.
E P, Brass, C L, Hoppel
openaire +2 more sources
A preliminary nontargeted lipidomics analysis reveals greater acylcarnitine in dark-cutting beef longissimus lumborum across visual severity levels. [PDF]
Harr KM +7 more
europepmc +1 more source
Incidental Detection of Glutamate Formiminotransferase Deficiency Through Newborn Screening in a Clinically Asymptomatic Infant: Molecular Findings and Counseling Considerations. [PDF]
Baheer Abdulwahhab S +2 more
europepmc +1 more source

