Results 21 to 30 of about 20,316 (189)

Gut Microbiota and Acylcarnitine Metabolites Connect the Beneficial Association between Estrogen and Lipid Metabolism Disorders in Ovariectomized Mice

Microbiology Spectrum, 2023
Decreased estrogen level is one of the main causes of lipid metabolism disorders and coronary heart disease in women after menopause. Exogenous estradiol benzoate is effective to some extent in alleviating lipid metabolism disorders caused by estrogen ...
Mengmeng Guo, Xi Cao, De Ji, Hui Xiong, Ting Zhang, Yujiang Wu, Langda Suo, Menghao Pan, Daniel Brugger, Yulin Chen, Ke Zhang, Baohua Ma   +11 more
doaj   +1 more source

Roux-en-Y Gastric Bypass Surgery Induces Distinct but Frequently Transient Effects on Acylcarnitine, Bile Acid and Phospholipid Levels

Metabolites, 2018
Roux-en-Y gastric bypass (RYGB) is an effective method to achieve sustained weight loss, but the mechanisms responsible for RYGB effects have not yet been fully characterized.
Jarlei Fiamoncini, Carina Fernandes Barbosa, José Rubens Arnoni Junior, José Celestino Araújo Junior, Cinthia Taglieri, Tiago Szego, Barbara Gelhaus, Heraldo Possolo de Souza, Hannelore Daniel, Thais Martins de Lima   +9 more
doaj   +1 more source

Direct Prediction of VLCADD Severity Using Newborn Screening Analyte Data. [PDF]

J Inherit Metab Dis
ABSTRACT A critical concern of newborn screening (NBS) for very‐long chain acyl‐CoA dehydrogenase deficiency (VLCADD) is the difficulty of predicting clinical outcomes. To address this, we investigated neonatal C18:2‐carnitine concentrations as a possible predictor of VLCADD phenotype.
Schwantje M, Maase RE, Dekkers E, Ferdinandusse S, Vaz FM, Hörster F, Mütze U, Grünert SC, Visser G, Velden MGMS, Fuchs SA.   +10 more
europepmc   +2 more sources

Features of carnitine metabolism in young athletes

Спортивная медицина: наука и практика, 2023
Objective: to study the indicators of carnitine metabolism in young athletes of various specializations.Materials and methods: This study involved 46 people with different levels of physical activity aged 15 to 18 years.
A. S. Samoilov, A. V. Zholinsky, N. V. Rylova, I. V. Bolshakov   +3 more
doaj   +1 more source

Acylcarnitines: Role in brain

Progress in Lipid Research, 2010
l-carnitine is present in mammalian cells as free carnitine and acylcarnitines. The acylcarnitine profile has been shown to be useful in identifying inborn errors of metabolism and to be altered under different metabolic conditions. While carnitine's most widely known function is its involvement in beta-oxidation of fatty acids, it may also have other ...
Department of Food Science and Human Nutrition, University of Florida, Gainesville, FL, United States ( host institution ), Jones, Lauren L. ( author ), McDonald, David A. ( author ), Borum, Peggy R. ( author )   +3 more
openaire   +3 more sources

The association between acylcarnitine and amino acids profile and metabolic syndrome and its components in Iranian adults: Data from STEPs 2016

Frontiers in Endocrinology, 2023
BackgroundEvidence, albeit with conflicting results, has suggested that cardiometabolic risk factors, including obesity, type 2 diabetes (T2D), dyslipidemia, and hypertension, are highly associated with changes in metabolic signature, especially plasma ...
Hananeh Taghizadeh, Solaleh Emamgholipour, Shaghayegh Hosseinkhani, Babak Arjmand, Negar Rezaei, Arezou Dilmaghani-Marand, Erfan Ghasemi, Nekoo Panahi, Hojat Dehghanbanadaki, Robabeh Ghodssi-Ghassemabadi, Niloufar Najjar, Mojgan Asadi, Mohsen khoshniat, Bagher Larijani, Farideh Razi   +14 more
doaj   +1 more source

Impaired acylcarnitine profile in transfusion-dependent beta-thalassemia major patients in Bangladesh

Journal of Advanced Research, 2018
Patients with beta-thalassemia major (BTM) suffer from fatigue, poor physical fitness, muscle weakness, lethargy, and cardiac complications which are related to an energy crisis.
Suprovath Kumar Sarker, Md Tarikul Islam, Golam Sarower Bhuyan, Nusrat Sultana, Mst. Noorjahan Begum, Mohammad Al Mahmud-Un-Nabi, Md. Abdulla Al Noman Howladar, Tashmim Farhana Dipta, A.K.M. Muraduzzaman, Syeda Kashfi Qadri, Tahmina Shirin, Salma Sadiya, Manzoor Hussain, Waqar Ahmed Khan, Sharif Akhteruzzaman, Syed Saleheen Qadri, Firdausi Qadri, Kaiissar Mannoor   +17 more
doaj   +1 more source

Acylcarnitines: Distinguishing acylcarnitine isomeric forms by HPLC/ESI/MS

The FASEB Journal, 2006
Isomeric acylcarnitines are indistinguishable by tandem mass spectrometry. This methodological deficiency can be overcome by including a chromatographic component in the analysis procedure. Isomeric acylcarnitines were synthesized and their pentafluorophenacyl esters chromatographed by HPLC and detected by ESI/MS using a quadrupole ion‐trap instrument.
Paul E. Minkler, Shuming Yang, Maria S.K. Stoll, Stephen T. Ingalls, Charles L. Hoppel   +4 more
openaire   +1 more source

Dynamic modelling of an ACADS genotype in fatty acid oxidation - Application of cellular models for the analysis of common genetic variants.

PLoS ONE, 2019
BACKGROUND:Genome-wide association studies of common diseases or metabolite quantitative traits often identify common variants of small effect size, which may contribute to phenotypes by modulation of gene expression.
Kerstin Matejka, Ferdinand Stückler, Michael Salomon, Regina Ensenauer, Eva Reischl, Lena Hoerburger, Harald Grallert, Gabi Kastenmüller, Annette Peters, Hannelore Daniel, Jan Krumsiek, Fabian J Theis, Hans Hauner, Helmut Laumen   +13 more
doaj   +1 more source

Review: Lipid biology in the periparturient dairy cow: contemporary perspectives

Animal, 2020
Coordinated changes in energy metabolism develop to support gestation and lactation in the periparturient dairy cow. Maternal physiology involves the partitioning of nutrients (i.e.
J.W. McFadden
doaj   +1 more source