Results 141 to 150 of about 1,339 (180)

Electrocarboxylation of aryl- and acylhydrazones in nonaqueous media

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1989
1. It is shown that a number of aryl and acylhydrazones can be electrochemically carboxylated in non-aqueous media (acetonitrile, DMF) to give α-hydrazino (or hydrazido) acids. 2. On passing from benzoyl to acetylhydrazones electrocarboxylation no longer occurs, probably because of the predominance in the acetylhydrazones of the EE′E ...
T. V. Troepol'skaya, G. A. Vagina, L. V. Ermolaeva, Z. S. Titova, T. A. Zyablikova, Yu. P. Kitaev   +5 more
openaire   +1 more source

Hydrazone, Benzohydrazones and Isoniazid-Acylhydrazones as Potential Antituberculosis Agents

Future Microbiology, 2019
Aim: To evaluate the potential of three benzohydrazones (1-3), four acylhydrazones derived from isoniazid (INH-acylhydrazones) (4-7) and one hydrazone (8) as antituberculosis agents. Materials & methods: Inhibitory and bactericidal activities were determined for the reference Mycobacterium tuberculosis (Mtb) strain and clinical isolates.
Eloísa G Sampiron, Giovana F Costacurta, Vanessa P Baldin, Aryadne L Almeida, Andressa L Ieque, Nathally C S Santos, Vanessa G Alves-Olher, Fábio Vandresen, Ana C R Gimenes, Vera L D Siqueira, Katiany R Caleffi-Ferracioli, Rosilene F Cardoso, Regiane B L Scodro   +12 more
openaire   +2 more sources

Acylhydrazone Derivatives: An Overview of Biological Activities

Current Bioactive Compounds
The N-acylhydrazone scaffold has emerged as a versatile pharmacophore in medicinal chemistry due to its ease of synthesis, structural flexibility, and broad-spectrum biological activity. This mini-review highlights recent advances in acylhydrazone-based therapeutics, with a focus on anticancer, antimicrobial ...
La Quy Luong, Pham Tran Khanh Linh, Chu Thi Hong Phuong, Nguyen Thi Ngoc Mai, Tran Khac Vu   +4 more
openaire   +1 more source

Synthesis and antitumor evaluation of oleanolic acid acylhydrazone derivatives

Molecular Diversity
Cancer is the second leading cause of death worldwide, highlighting the urgent need for novel therapeutic strategies and targeted drug development. Oleanolic acid (OA) is a natural compound with notable antitumor activity. This study aimed to develop OA derivatives with enhanced antitumor potency through structural optimization and biological ...
Juan, Cai, Bo-Wen, Pan, Liang-Liang, Zheng, You-Ping, Tian, Zhang-Chao, Dong, Li-Juan, Liu, Ting-Ting, Feng, Ying, Zhou, Xiong-Wei, Liu, Yang, Shi   +9 more
openaire   +2 more sources

On Acylhydrazones and 1,2,3-Thiadiazoles

Journal of the American Chemical Society, 1955
Charles D. Hurd, Raymond I. Mori
openaire   +1 more source

Asymmetric Allylation of Acylhydrazones

Synfacts, 2007
E. Jacobsen, K. Tan
openaire   +1 more source

Allylation of Acylhydrazones

2012
T. Inokuma, Y. Takemoto
openaire   +1 more source

Anticancer agents incorporating the N‐acylhydrazone scaffold: Progress from 2017 to present

Archiv Der Pharmazie, 2023
Asmaâ Kassab
exaly  

First Synthesis of Betulin 20-Acylhydrazones

Russian Journal of Organic Chemistry, 2022
Yu. V. Myasoedova, E. R. Belyaeva, L. R. Garifullina, D. A. Prosvirnina, G. Yu. Ishmuratov   +4 more
openaire   +1 more source

Synthesis and Biological Activity of N-Acylhydrazones

Russian Journal of Bioorganic Chemistry, 2022
E. R. Belyaeva, Yu. V. Myasoedova, N. M. Ishmuratova, G. Yu. Ishmuratov   +3 more
openaire   +1 more source