Results 161 to 170 of about 2,678 (221)

Exploring the Conformational Effects of <i>N</i>- and <i>C</i>-Methylation of <i>N</i>-Acylhydrazones. [PDF]

ACS Omega
Franco LS, Alves MA, Sant'Anna CMR, de Sena Bastos IT, Barroso RCR, Costa FN, Ferreira FF, Fraga CAM, Barreiro EJ, Lima LM, Rodrigues DA, Pinheiro PSM.   +11 more
europepmc   +1 more source

Evaluation of hydrazone and N-acylhydrazone derivatives of vitamin B6 and pyridine-4-carbaldehyde as potential drugs against Alzheimer's disease. [PDF]

J Enzyme Inhib Med Chem
Bartolić M, Matošević A, Maraković N, Bušić V, Roca S, Vikić-Topić D, Sabljić A, Bosak A, Gašo-Sokač D.   +8 more
europepmc   +1 more source

Iron-Based Nanoparticles as Delivery Tools. [PDF]

Pharmaceuticals (Basel)
Parang K, Vadlapatla R, Koomer A, Moran V, Jackson L, Shirazi AN.   +5 more
europepmc   +1 more source

Studies on metal complexes with acylhydrazones based on heterocyclic carbonyl compounds

, 2010
S.R. Sheeja, M R Dr.Prathapachandra Kurup   +1 more
openalex   +1 more source

Design, Synthesis, and Bioactivity Assessment of Modified Vemurafenib Analog. [PDF]

Pharmaceuticals (Basel)
Guerra FS, Freitas RHCN, Moldovan F, Rocha DRD, Carvalho RS, Fernandes PD.   +5 more
europepmc   +1 more source

Injectable, self-healing and degradable dynamic hydrogels with tunable mechanical properties and stability by thermal-induced micellization. [PDF]

RSC Adv
Lin C, Chen L, He Y, Xiang W, Nie Y, Cai B, Guo Z.   +6 more
europepmc   +1 more source

A new <i>N</i>-acylhydrazone oxadiazole derivative with activity against mycobacteria. [PDF]

Future Microbiol
Souza IV, Fróes da Motta Dacome ML, Frederico Rozada AM, Rosa JS, Sampiron EG, Ferreira DG, Gauze GF, Norman Negri MF, de Lima Scodro RB, Cardoso RF, Caleffi-Ferracioli KR.   +10 more
europepmc   +1 more source

Design, Synthesis, and Biological Evaluation of <i>N</i>-Acylhydrazones and Their Activity Against <i>Leishmania amazonensis</i> Promastigotes. [PDF]

Microorganisms
Oliveira Monteiro CE, Martins Mafra JC, Boechat N, Silva ERD.   +3 more
europepmc   +1 more source

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Acylhydrazone derivatives: a patent review

Expert Opinion on Therapeutic Patents, 2014
The N-acylhydrazone (NAH) moiety has been characterized as a privileged structure, capable of providing ligands points for more than one type of bioreceptor. Modifications of the subunits bonded to its acyl and imine functions resulted in several derivatives, which modulate a great diversity of molecular targets.
Rodolfo Do Couto Maia, Roberta Tesch, CARLOS A M Fraga   +2 more
exaly   +3 more sources

N-Acylhydrazones as drugs

Bioorganic & Medicinal Chemistry Letters, 2018
Over the last two decades, N-acylhydrazone (NAH) has been proven to be a very versatile and promising motif in drug design and medicinal chemistry. Herein, we discuss the current and future challenges in the emergence of bioactive NAH-based scaffolds and to developing strategies to overcome the failures in drug discovery. The NAH-related approved drugs
Sreekanth, Thota, Daniel A, Rodrigues, Pedro de Sena Murteira, Pinheiro, Lídia M, Lima, Carlos A M, Fraga, Eliezer J, Barreiro   +5 more
openaire   +2 more sources