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Catalytic hydrophosphorylation of alkyl- and acylhydrazones

Russian Chemical Bulletin, 2010
N-Boc- and N-acylhydrazino phosphonates were obtained for the first time by hydrophosphorylation of the appropriate hydrazones of aliphatic and aromatic aldehydes and heterocyclic and aliphatic ketones in the presence of [tetra(tert-butyl)phthalocyanine]aluminum chloride as a catalyst.
E. D. Matveeva   +5 more
openaire   +1 more source

Synthesis and application of hypochlorite mediated acylhydrazone fluorescence probes

Luminescence, 2023
AbstractHypochlorous acid (HClO/ClO−) is one of the important reactive oxygen species (ROS). It acts as a second signaling molecule within and between cells and is an indispensable active molecule in living organisms to regulate physiological and pathological processes.
Chenglu Zhang   +4 more
openaire   +2 more sources

Triphenyltin(IV) acylhydrazone compounds: Synthesis, structure and bioactivity

Journal of Inorganic Biochemistry, 2019
Four new triphenyltin(IV) acylhydrazone compounds of the type Ph3SnCH2CH2CONHN=R (where Ph = phenyl; R = isopropyl, isobutyl, cyclopentyl and cyclooctyl) were synthesized and characterized by elemental analysis, infrared spectrum (IR), nuclear magnetic resonance spectrum (NMR) and mass spectrum (MS).
Xicheng, Liu   +9 more
openaire   +2 more sources

Stimuli-Responsive Anion Transport through Acylhydrazone-Based Synthetic Anionophores

Organic Letters, 2021
Photoswitchable acylhydrazone-based synthetic anionophores are reported. Single-crystal X-ray structure and 1H NMR titration studies confirmed the chloride binding in solid and solution states. The ion transport activity of 1a was greatly attenuated through a phototriggered E to Z photoisomerization process, and the photoisomerized deactivated state ...
Manzoor Ahmad   +4 more
openaire   +2 more sources

Crystalline Acylhydrazone Photoswitches with Multiple Mechanical Responses

Crystal Growth & Design, 2019
The advancement of our understanding of stimuli-responsive molecular crystals has led to the realization that they hold great yet unexplored potential as adaptive materials. Although molecular crystals that exhibit a single mechanical response to a single input stimulus are now abundant, crystals that are capable of response to multiple stimuli are ...
Poonam Gupta   +8 more
openaire   +1 more source

ChemInform Abstract: Acylhydrazones of Cyclopentanone‐2‐carboxylates.

ChemInform, 1992
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
F. V. BAGROV, A. S. MOLCHADSKII
openaire   +1 more source

Antiproliferative Activity of 8-methoxy Ciprofloxacin-Hydrozone/Acylhydrazone Scaffolds

Current Topics in Medicinal Chemistry, 2020
Aims: A series of 8-methoxy ciprofloxacin- hydrazone/acylhydrazone hybrids were evaluated for their activity against a panel of cancer cell lines including HepG2 liver cancer cells, MCF-7, doxorubicin- resistant MCF-7 (MCF-7/DOX) breast cancer cells, DU-145 and multidrug-resistant DU145 (MDR DU-145) prostate cancer cells to seek for novel anticancer ...
Li-Ping, Wang   +3 more
openaire   +2 more sources

Acylhydrazones as M1/M3 selective muscarinic agonists

Bioorganic & Medicinal Chemistry Letters, 1996
Abstract To improve receptor binding affinity and to investigate functional selectivity of 2,8-dimethyl-1-oxa-8-azaspiro[4.5]decan-3-one acetylhydrazone 2 at muscarinic receptor subtypes, a series of acylhydrazones A was synthesized. The SAR indicates that the binding affinity in the pirenzepine assay (M1) correlates well with lipophilicity ...
Edwin S.C. Wu   +10 more
openaire   +1 more source

Antiparasitic activities of novel pyrimidine N‐acylhydrazone hybrids

Drug Development Research, 2020
AbstractIn this article, a series of 29 new pyrimidine N‐acylhydrazone hybrids were synthesized and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi protozoa that cause the neglected diseases cutaneous leishmaniasis and Chagas disease, respectively.
Julia Poletto   +6 more
openaire   +2 more sources

Palladium-Catalyzed Multicomponent Carbonylation of Halides to Acylhydrazones

The Journal of Organic Chemistry
The current methods for synthesizing acylhydrazones are limited by their multistep processes, narrow substrate scope, low selectivities, and poor yields. Herein, a fundamentally novel approach to bioactive acylhydrazones was developed based on the palladium-catalyzed multicomponent tandem condensation carbonylation of halides with aldehydes and ...
Qianqian Liang   +3 more
openaire   +2 more sources

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