Results 181 to 190 of about 2,678 (221)

The solid state VCD of a novel N-acylhydrazone trifluoroacetate

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022
A novel N-acylhydrazone with pharmaceutical importance was subject of structural and IR/VCD investigations in the solid state. In the crystal structure, dimers of anion-cation pairs are stabilized by H-bonding and ionic interactions. Some less common interaction types, like C=N···C-NH3+ (σ-hole) interactions, hydrazone-aromatic interactions and ...
Joanna E, Rode, Krzysztof, Lyczko, Katarzyna, Kosińska, Joanna, Matalińska, Jolanta, Dyniewicz, Aleksandra, Misicka, Jan Cz, Dobrowolski, Piotr F J, Lipiński   +7 more
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Design, Synthesis and in vitro Antimalarial Activity of an Acylhydrazone Library.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Melnyk, Patricia, Leroux, Virginie, Sergheraert, Christian, Grellier, Philippe   +3 more
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Synthesis and Antibacterial Activity of Erythromycin 9-Acylhydrazone Derivates

Medicinal Chemistry, 2023
Background: Some species of Marine bacteria pose great risks to human and mariculture organisms. Meanwhile, Vibrio harveyi and Vibrio parahaemolyticus strains have acquired resistance to many antibiotics. Objective: A novel series of erythromycin 9-acylhydrazone derivatives were synthesized and evaluated for their in vitro antibacterial activity ...
Zhiling, Cao, Wei, Zheng, Maolong, Huang, Xinran, Yao, Wenrong, Zhu, Lanjun, Sheng, Zaixiu, Pan, Yuzong, Bian, Tian, Zhang, Cong, Zhu   +9 more
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Electrocarboxylation of aryl- and acylhydrazones in nonaqueous media

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1989
1. It is shown that a number of aryl and acylhydrazones can be electrochemically carboxylated in non-aqueous media (acetonitrile, DMF) to give α-hydrazino (or hydrazido) acids. 2. On passing from benzoyl to acetylhydrazones electrocarboxylation no longer occurs, probably because of the predominance in the acetylhydrazones of the EE′E ...
T. V. Troepol'skaya, G. A. Vagina, L. V. Ermolaeva, Z. S. Titova, T. A. Zyablikova, Yu. P. Kitaev   +5 more
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Palladium-Catalyzed Multicomponent Carbonylation of Halides to Acylhydrazones

The Journal of Organic Chemistry
The current methods for synthesizing acylhydrazones are limited by their multistep processes, narrow substrate scope, low selectivities, and poor yields. Herein, a fundamentally novel approach to bioactive acylhydrazones was developed based on the palladium-catalyzed multicomponent tandem condensation carbonylation of halides with aldehydes and ...
Qianqian Liang, Shuo Gao, Wentao Hao, Guoying Zhang   +3 more
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Hydrazone, Benzohydrazones and Isoniazid-Acylhydrazones as Potential Antituberculosis Agents

Future Microbiology, 2019
Aim: To evaluate the potential of three benzohydrazones (1-3), four acylhydrazones derived from isoniazid (INH-acylhydrazones) (4-7) and one hydrazone (8) as antituberculosis agents. Materials & methods: Inhibitory and bactericidal activities were determined for the reference Mycobacterium tuberculosis (Mtb) strain and clinical isolates.
Eloísa G Sampiron, Giovana F Costacurta, Vanessa P Baldin, Aryadne L Almeida, Andressa L Ieque, Nathally C S Santos, Vanessa G Alves-Olher, Fábio Vandresen, Ana C R Gimenes, Vera L D Siqueira, Katiany R Caleffi-Ferracioli, Rosilene F Cardoso, Regiane B L Scodro   +12 more
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Triphenyltin(IV) acylhydrazone compounds: Synthesis, structure and bioactivity

Journal of Inorganic Biochemistry, 2019
Four new triphenyltin(IV) acylhydrazone compounds of the type Ph3SnCH2CH2CONHN=R (where Ph = phenyl; R = isopropyl, isobutyl, cyclopentyl and cyclooctyl) were synthesized and characterized by elemental analysis, infrared spectrum (IR), nuclear magnetic resonance spectrum (NMR) and mass spectrum (MS).
Xicheng, Liu, Yanhua, Tang, Xiangdong, He, Xingxing, Ge, Jiao, Liu, Xiaoyu, Meng, Mingxiao, Shao, Yingmin, Jin, Laijin, Tian, Zhe, Liu   +9 more
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A tetraphenylethylene-based acylhydrazone gel for selective luminescence sensing

Chemical Communications, 2018
A supramolecular gel based on dynamic covalent acylhydrazone bonding for selective and sensitive Cu2+and subsequent CN−detection has been reported.
Haobin Fang, Guangmei Cai, Ya Hu, Jianyong Zhang   +3 more
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Acylhydrazone Derivatives: An Overview of Biological Activities

Current Bioactive Compounds
Abstract: The N-acylhydrazone scaffold has emerged as a versatile pharmacophore in medicinal chemistry due to its ease of synthesis, structural flexibility, and broad-spectrum biological activity. This mini-review highlights recent advances in acylhydrazone-based therapeutics, with a focus on anticancer, antimicrobial, and anti-inflammatory ...
La Quy Luong, Pham Tran Khanh Linh, Chu Thi Hong Phuong, Nguyen T hi Ngoc Mai, Tran Khac Vu   +4 more
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Crystalline Acylhydrazone Photoswitches with Multiple Mechanical Responses

Crystal Growth & Design, 2019
The advancement of our understanding of stimuli-responsive molecular crystals has led to the realization that they hold great yet unexplored potential as adaptive materials. Although molecular crystals that exhibit a single mechanical response to a single input stimulus are now abundant, crystals that are capable of response to multiple stimuli are ...
Poonam Gupta, Tamas Panda, Suryanarayana Allu, Silpisikha Borah, Anamika Baishya, Anilkumar Gunnam, Ashwini Nangia, Panče Naumov, Naba K. Nath   +8 more
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