Results 171 to 180 of about 3,211 (225)

Self-aggregation of zinc bacteriochlorophyll-d analogs with an acylhydrazone moiety as the 13-keto-carbonyl alternative. [PDF]

Photochem Photobiol
Fujii S, Tamiaki H.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Acylhydrazone derivatives: a patent review

Expert Opinion on Therapeutic Patents, 2014
The N-acylhydrazone (NAH) moiety has been characterized as a privileged structure, capable of providing ligands points for more than one type of bioreceptor. Modifications of the subunits bonded to its acyl and imine functions resulted in several derivatives, which modulate a great diversity of molecular targets.
Rodolfo do Couto Maia, Roberta Tesch, Carlos Fraga   +2 more
exaly   +3 more sources

N-Acylhydrazones as drugs

Bioorganic & Medicinal Chemistry Letters, 2018
Over the last two decades, N-acylhydrazone (NAH) has been proven to be a very versatile and promising motif in drug design and medicinal chemistry. Herein, we discuss the current and future challenges in the emergence of bioactive NAH-based scaffolds and to developing strategies to overcome the failures in drug discovery. The NAH-related approved drugs
Sreekanth, Thota, Daniel A, Rodrigues, Pedro de Sena Murteira, Pinheiro, Lídia M, Lima, Carlos A M, Fraga, Eliezer J, Barreiro   +5 more
openaire   +2 more sources

Acylhydrazones as Widely Tunable Photoswitches

Journal of the American Chemical Society, 2015
Molecular photoswitches have attracted much attention in biological and materials contexts. Despite the fact that existing classes of these highly interesting functional molecules have been heavily investigated and optimized, distinct obstacles and inherent limitations remain.
Derk Jan van Dijken, † Petr Kovaříček, ‡ Svante P. Ihrig, and Stefan Hecht*   +3 more
openaire   +2 more sources

Discovery of novel acylhydrazone neuraminidase inhibitors

European Journal of Medicinal Chemistry, 2019
Neuraminidase (NA) plays a crucial role in the replication and transmission of influenza virus. NA inhibitors have been developed as effective treatments for influenza A and B infections. In this paper, a new lead neuraminidase inhibitor 6a (IC50 = 7.10 ± 0.2 μM) was discovered by ligand-based virtual screening, receptor-based virtual screening ...
Zhi Xiang Zhao, Li Ping Cheng, Meng Li, Wan Pang, Fan Hong Wu   +4 more
openaire   +2 more sources

Strecker Reactions of Chiral N‐Acylhydrazones.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Gregory K. Friestad, Hui Ding
openaire   +1 more source

D-arabino-hexosulose bis(acylhydrazones) and 2-acylhydrazone 1-arylhydrazones

Carbohydrate Research, 1967
Abstract D - arabino -Hexosulose bis(acylhydrazones) ( 1–4 ), 2-acylhydrazone 1-phenylhydrazones ( 5–16 ), and 2-acylhydrazone 1-(2-methyl-2-phenyl)hydrazones ( 17–24 ) were prepared from D - arabino -hexosulose or its hydrazone and acylhydrazines. The properties of these osazones were compared with those of arylosazones and bis(benzoylhydrazones).
H. El Khadem, M.A.E. Shaban
openaire   +1 more source

N-Acylhydrazones as inhibitors of PDE10A

Bioorganic & Medicinal Chemistry Letters, 2011
Cyclic nucleotide phosphodiesterases (PDEs) are represented by a large superfamily of enzymes. A series of hydrazone-based inhibitors was synthesized and shown to be novel, potent, and selective against PDE10A. Optimized compounds of this class were efficacious in animal models of schizophrenia and may be useful for the treatment of this disease.
Jennifer L, Gage, Rene, Onrust, Derek, Johnston, Andrew, Osnowski, Wendy, Macdonald, Lee, Mitchell, László, Urögdi, Alex, Rohde, Kevin, Harbol, Sasha, Gragerov, György, Dormán, Tom, Wheeler, Vince, Florio, Neil S, Cutshall   +13 more
openaire   +2 more sources

Some ferrocene derivatives of acylhydrazones

Wuhan University Journal of Natural Sciences, 1998
The title organometallic compounds were synthesized by the condensation of formyl and acetyl ferrocene with cyanoacetyl, propionyl, butyryl,o-furoyl,o-thiofuroyl andm-pyridinecarboxy hydrazine in anhydrous ethanol under reflux. The IR,1H NMR, MS, and Mossbauer spectra for these compounds were recorded and are discussed.
Ding Zirong, Peng Chen, Zhang Lun, Zhao Qingbo, Chen Sunian, Qi Shoure   +5 more
openaire   +1 more source

Phenyliodonium diacetate mediated carbotrifluoromethylation of N-acylhydrazones

Organic & Biomolecular Chemistry, 2016
A concise, efficient and direct trifluoromethylation method of aldehyde-derivedN-acylhydrazones has been firstly developed by using the combination of inexpensive, stable and commercially available TMSCF3and PhI(OAc)2as the CF3source under mild reaction conditions.
Weigang Zhang, Yingpeng Su, Siying Chong, Lili Wu, Guiyan Cao, Danfeng Huang, Ke-Hu Wang, Yulai Hu   +7 more
openaire   +2 more sources