Results 121 to 130 of about 63,314 (347)

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

Role of plasma lecithin:cholesterol acyltransferase in the metabolism of high density lipoproteins

Journal of Lipid Research, 1966
The role of the plasma lecithin:cholesterol acyltransferase reaction in the esterification of the cholesterol of human and baboon plasma high density lipoproteins has been studied.Human plasma was incubated in vitro, and the initial rate of cholesterol ...
J.A. Glomset, E.T. Janssen, R. Kennedy, J. Dobbins   +3 more
doaj  

Catalytic properties of MGAT3, a putative triacylgycerol synthases⃞

Journal of Lipid Research, 2007
Acyl-coenzyme A:monoacylglycerol acyltransferase 3 (MGAT3) is a member of the MGAT family of enzymes that catalyze the synthesis of diacylglycerol (DAG) from monoacylglycerol (MAG), a committed step in dietary fat absorption.
Jingsong Cao, Long Cheng, Yuguang Shi
doaj  

Diacylglycerol Acyltransferase-2 (DGAT2) and Monoacylglycerol Acyltransferase-2 (MGAT2) Interact to Promote Triacylglycerol Synthesis*

Journal of Biological Chemistry, 2014
Background: DGAT2 catalyzes the final and committed step of triacylglycerol (TG) biosynthesis. Results: Co-immunoprecipitation experiments and in situ proximity ligation assays showed that DGAT2 and MGAT2 interact.
Youzhi Jin, P. J. McFie, S. Banman, C. Brandt, S. Stone   +4 more
semanticscholar   +1 more source

Comparative analyses of isoforms of the calcium-independent phosphatidylethanolamine N-acyltransferase PLAAT-1 in humans and mice

Journal of Lipid Research, 2016
N-Acylphosphatidylethanolamines (NAPEs) are a class of glycerophospholipids, which are known as precursors for different bioactive N-acylethanolamines. We previously reported that phospholipase A/acyltransferase-1 (PLAAT-1), which was originally found in
Zahir Hussain, Toru Uyama, Katsuhisa Kawai, Iffat Ara Sonia Rahman, Kazuhito Tsuboi, Nobukazu Araki, Natsuo Ueda   +6 more
doaj  

The Subcellular Distribution of Acyltransferases which Catalyze the Synthesis of Phosphoglycerides [PDF]

, 1969
H. Eibl, Edward E. Hill, William E.M. Lands   +2 more
openalex   +1 more source

Improvement of Neutral Lipid and Polyunsaturated Fatty Acid Biosynthesis by Overexpressing a Type 2 Diacylglycerol Acyltransferase in Marine Diatom Phaeodactylum tricornutum

Marine Drugs, 2013
Microalgae have been emerging as an important source for the production of bioactive compounds. Marine diatoms can store high amounts of lipid and grow quite quickly.
Y. Niu, Meng-Han Zhang, Da-wei Li, Wei-dong Yang, Jie‐sheng Liu, Weibin Bai, Hong-ye Li   +6 more
semanticscholar   +1 more source

Lipid Metabolism and Immune Function: Chemical Tools for Insights into T‐Cell Biology

ChemBioChem, EarlyView.
This review explores how lipids regulate immune responses, particularly in T‐cell function. Advances in metabolomics and proteomics provide insights into lipid‐mediated immunity. Fluorescent lipids enable single‐cell analysis of lipid uptake and metabolism.
Luuk Reinalda, Mario van der Stelt, Sander Izaak van Kasteren   +2 more
wiley   +1 more source

Prognostic significance of cytoskeleton‐associated membrane protein 4 and its palmitoyl acyltransferase DHHC2 in hepatocellular carcinoma

Cancer, 2014
The functions of cytoskeleton‐associated membrane protein 4 (CKAP4), one kind of type II transmembrane protein, are associated with the palmitoyl acyltransferase DHHC2.
Shuang-xi Li, G. Tang, Dong-xun Zhou, Yu-Fei Pan, Ye-Xiong Tan, Jian Zhang, Bo Zhang, Zhi‐wen Ding, Li-juan Liu, T. Jiang, He-ping Hu, Liwei Dong, Hong-Yang Wang   +12 more
semanticscholar   +1 more source

First Steps toward the Design of Peptides that Influence the Intracellular Palmitoylation Machinery

ChemBioChem, EarlyView.
Herein, DC peptides consisting of the cell‐penetrating peptide sC18* and a Asp–His–His–Cys (DHHC) motif derived from human ZDHHC palmitoyltransferase are highlighted. DC peptides demonstrate high cellular internalization into various cellular models, exert cytotoxic effects against cancerous cells, and alter the function and localization of known ...
Katharina Stillger, Eric Platz‐Baudin, Florian Friedland, Melina Ruppel, Coco‐Louisa Sticker, Anne Bodenhausen, Erik Noetzel, Ines Neundorf   +7 more
wiley   +1 more source