Results 101 to 110 of about 58,776 (313)

Variant frequencies and deleterious score predictions of carnitine acyltransferase genes. [PDF]

open access: yes, 2015
Variant frequencies and deleterious score predictions of carnitine acyltransferase genes.
Amirthagowri Ambalavanan (651834)   +11 more
core   +1 more source

Identification of an SCPL Gene Controlling Anthocyanin Acylation in Carrot (Daucus carota L.) Root

open access: yesFrontiers in Plant Science, 2020
Anthocyanins are natural health promoting pigments that can be produced in large quantities in some purple carrot cultivars. Decoration patterns of anthocyanins, such as acylation, can greatly influence their stability and biological properties and use ...
Julien Curaba   +11 more
doaj   +1 more source

Mitochondrial acyltransferases and glycerophospholipid metabolism

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2017
Our understanding of the synthesis and remodeling of mitochondrial phospholipids remains incomplete. Two isoforms of glycerol-3-phosphate acyltransferase (GPAT1 and 2) and two isoforms of acylglycerol-3-phosphate acyltransferase (AGPAT4 and 5) are located on the outer mitochondrial membrane, suggesting that both lysophosphatidic acid and phosphatidic ...
Coleman, Rosalind A.   +1 more
openaire   +3 more sources

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

open access: yesAdvanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su   +4 more
wiley   +1 more source

Coding variants of carnitine acyltransferase genes discovered in Nunavik Inuit. [PDF]

open access: yes, 2015
Coding variants of carnitine acyltransferase genes discovered in Nunavik Inuit.
Amirthagowri Ambalavanan (651834)   +11 more
core   +1 more source

Acyltransferases Regulate Oil Quality in Camelina sativa Through Both Acyl Donor and Acyl Acceptor Specificities

open access: yesFrontiers in Plant Science, 2020
Camelina sativa is an emerging biotechnology oil crop. However, more information is needed regarding its innate lipid enzyme specificities. We have therefore characterized several triacylglycerol (TAG) producing enzymes by measuring in vitro substrate ...
Ida Lager   +7 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

Mining the active proteome of Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2011
Assigning functions to the >30.000 proteins encoded by the Arabidopsis genome is a challenging task of the Arabidopsis Functional Genomics Network.
Renier A. L. Van Der Hoorn   +5 more
doaj   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

open access: yesAdvanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt   +16 more
wiley   +1 more source

Diacylglycerol Acyltransferase Sequences and Related Methods [PDF]

open access: yes, 2013
Isolated nucleic acid and amino acid sequences encoding a diacylglycerol acyltransferase 2 (DGAT2) polypeptide are provided. Vectors and transgenic cells that include a nucleic acid sequence encoding a DGAT2 polypeptide are also described.
Hildebrand, David   +2 more
core   +1 more source

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