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The role of lysine acylation in metabolic dysregulation and inflammatory responses within the hepatic immune microenvironment of MASLD [PDF]
Frontiers in ImmunologyMetabolic dysfunction–associated steatotic liver disease (MASLD) is a chronic liver disorder characterized by metabolic abnormalities, persistent low-grade inflammation, and alterations in hepatic immune function.
Jingyi Peng +8 more
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Regulatory effects of protein S-acylation on insulin secretion and insulin action [PDF]
Open Biology, 2021 Post-translational modifications (PTMs) such as phosphorylation and ubiquitination are well-studied events with a recognized importance in all aspects of cellular function.
Luke H. Chamberlain +2 more
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Frontiers in Plant Science, 2022 Protein S-acylation, also known as palmitoylation, is an important lipid post-translational modification of proteins in eukaryotes. S-acylation plays critical roles in a variety of protein functions involved in plant development and responses to abiotic ...
Jincheng Li, Manqi Zhang, Lijuan Zhou
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Lysine Fatty Acylation: Regulatory Enzymes, Research Tools, and Biological Function
Frontiers in Cell and Developmental Biology, 2021 Post-translational acylation of lysine side chains is a common mechanism of protein regulation. Modification by long-chain fatty acyl groups is an understudied form of lysine acylation that has gained increasing attention recently due to the ...
Garrison Komaniecki +4 more
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Food Technology and Biotechnology, 2022 Research background. Anthocyanins possess valuable health-promoting activities with significant health benefits for humans. However, their instability is a limiting factor for their usage in functional foods and beverages. Experimental approach. In this
Bei Zhang +7 more
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Redox-neutral C–H acylation of indole with ketene by manganese catalysis
Green Synthesis and Catalysis, 2022 A low-cost manganese-catalyzed oxidant-free selective C–H acylation of indole with ketene is reported. This protocol features mild reaction conditions and good functional group tolerance. The yield is from middle to excellent.
Chengming Wang, Qijing Zhang
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Catalysis Communications, 2023 In this study, we describe the synthesis of an efficient catalyst for the acylation of alcohols, phenols, and amines in the presence of 3,3′-(ethane-1,2-diyl)bis(1-methyl-1H-imidazol-3-ium) tetrachloroferrate [DIL]2+[2FeCl4]2− and acetyl chloride ...
Yash Barot +3 more
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Biological functions and therapeutic potential of acylation by histone acetyltransferases
Acta Materia Medica, 2023 Histone lysine acylation is a major class of histone post-translational modifications involved in essential biological activities, such as transcriptional regulation, DNA-damage repair, and cell-cycle progression.
Nan Li +6 more
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Journal of the Turkish Chemical Society, Section A: Chemistry, 2017 There are quite many examples in the scientific literature regarding the acylation reactions, especially the metal-catalyzed acylation reactions, metal-free acylation reactions, metal-catalyzed acylation via cross-dehydrogenative coupling (CDC) reactions
Soykan Ağar, Ömer Tahir Günkara
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SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a
eLife, 2017 Ras proteins play vital roles in numerous biological processes and Ras mutations are found in many human tumors. Understanding how Ras proteins are regulated is important for elucidating cell signaling pathways and identifying new targets for treating ...
Hui Jing +6 more
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