Results 21 to 30 of about 89,225 (346)
, 2023 Acylation reaction belongs to the most desired transformation by chemists because of its wide application for industrial scale synthesis of fine chemicals and pharmaceuticals.
Mannepalli, Lakshmi Kantam +4 more
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meta-Selective Radical Acylation of Electron-rich Arenes [PDF]
, 2023 meta-Selective functionalisation of electron-rich arenes provides a non-traditional route to organic synthesis. In classical electrophilic aromatic substitution of electron-donating group-pendant arenes, functionalisation occurs according to ortho- and ...
Masaki , Sano +3 more
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Biological functions and therapeutic potential of acylation by histone acetyltransferases
Acta Materia Medica, 2023 Histone lysine acylation is a major class of histone post-translational modifications involved in essential biological activities, such as transcriptional regulation, DNA-damage repair, and cell-cycle progression.
Nan Li +6 more
doaj +1 more source
bioRxiv, 2022 Protein S-acylation is a reversible post-translational modification that modulates the localisation and function of many cellular proteins. S-acylation is mediated by a family of zinc finger DHHC domain-containing proteins encoded by 23 distinct ZDHHC ...
C. Salaun +8 more
semanticscholar +1 more source
Cleaner Routes for Friedel-Crafts Acylation [PDF]
, 2010 Friedel-Crafts acylation is among the most fundamental and useful reactions to yield aromatic ketones but it is one of the less acceptable in terms of unwanted polluting by-products or atom economy because of the overconsumption of catalyst which is used
Aribert, Nicolas +4 more
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Journal of the Turkish Chemical Society, Section A: Chemistry, 2017 There are quite many examples in the scientific literature regarding the acylation reactions, especially the metal-catalyzed acylation reactions, metal-free acylation reactions, metal-catalyzed acylation via cross-dehydrogenative coupling (CDC) reactions
Soykan Ağar, Ömer Tahir Günkara
doaj +1 more source
Microcosmic Mechanism of Dication for Inhibiting Acylation of Acidic Peptide [PDF]
, 2015 For long-effective peptide formulation based on poly(d,l-lactic-co-glycolic acid) (PLGA) microspheres, acylation often leads to peptide instability during its release and reduced drug efficacy.
Qi, Feng +4 more
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SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a
eLife, 2017 Ras proteins play vital roles in numerous biological processes and Ras mutations are found in many human tumors. Understanding how Ras proteins are regulated is important for elucidating cell signaling pathways and identifying new targets for treating ...
Hui Jing +6 more
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Optimization of the Enzymatic Acylation Reaction Conditions of Vitis davidii Malvidin
Shipin gongye ke-ji, 2022 In order to increase the structural stability of anthocyanins, taking Vitis davidii malvidin as sample and the lipase CAL-B as catalyst, the effects of reaction time, temperature, and substrate molar ratio on enzymatic acylation were investigated.
Aili CAI +5 more
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Development of an Acrylamide-Based Inhibitor of Protein S-Acylation
ACS Chemical Biology, 2021 Protein S-acylation is a dynamic lipid post-translational modification that can modulate the localization and activity of target proteins. In humans, the installation of the lipid onto target proteins is catalyzed by a family of 23 Asp-His-His-Cys domain-
S. Azizi +8 more
semanticscholar +1 more source