Results 31 to 40 of about 60,893 (292)

‐Acylation [PDF]

open access: yes, 2016
A catalytic enantioselective route to C1- and C2- symmetric 2,2ʹ-spirobiindanones has been realized through an intramolecular enolate C-acylation. This reaction employs a chiral ammonium counterion to direct the acylation of an in situ generated ketone ...
Clark, Hugh F.   +8 more
core   +1 more source

Function of Protein S-Palmitoylation in Immunity and Immune-Related Diseases

open access: yesFrontiers in Immunology, 2021
Protein S-palmitoylation is a covalent and reversible lipid modification that specifically targets cysteine residues within many eukaryotic proteins. In mammalian cells, the ubiquitous palmitoyltransferases (PATs) and serine hydrolases, including acyl ...
Yuqi Zhang   +4 more
doaj   +1 more source

Detection of S-Acylated CD95 by Acyl-Biotin Exchange [PDF]

open access: yes, 2017
S-acylation is the covalent addition of a fatty acid, most generally palmitate onto cysteine residues of proteins through a labile thioester linkage. The death receptor CD95 is S-palmitoylated and this post-translational modification plays a crucial role on CD95 organization in cellular membranes and thus on CD95-mediated signaling.
Rossin, Aurelie, Hueber, Anne-Odile
openaire   +2 more sources

Microcosmic Mechanism of Dication for Inhibiting Acylation of Acidic Peptide

open access: yes, 2015
For long-effective peptide formulation based on poly(d,l-lactic-co-glycolic acid) (PLGA) microspheres, acylation often leads to peptide instability during its release and reduced drug efficacy.
Qi, Feng   +4 more
core   +1 more source

Thermomyces lanuginosus lipase-catalyzed regioselective acylation of nucleosides: Enzyme substrate recognition

open access: yes, 2009
Substrate recognition of Thermomyces lanuginosus lipase in the acylation of nucleosides was revealed through rational substrate engineering for the first time. T lanuginosus lipase displayed higher catalytic activities and excellent 5'-regioselectivities
Li, Ning   +4 more
core   +1 more source

Assaying protein palmitoylation in plants

open access: yesPlant Methods, 2008
Background Protein S-acylation (also known as palmitoylation) is the reversible post-translational addition of acyl lipids to cysteine residues in proteins through a thioester bond. It allows strong association with membranes.
Taylor Laura   +2 more
doaj   +1 more source

Homeoviscous Adaptation of the Acinetobacter baumannii Outer Membrane: Alteration of Lipooligosaccharide Structure during Cold Stress

open access: yesmBio, 2021
To maintain optimal membrane dynamics, cells from all domains of life must acclimate to various environmental signals in a process referred to as homeoviscous adaptation.
Carmen M. Herrera   +2 more
doaj   +1 more source

N-Acylation of Oxazolidinones via Aerobic Oxidative NHC Catalysis [PDF]

open access: yes, 2018
In the ongoing quest to find alternatives to atom un-economical and forcing conditions in acylation reactions, aerobic oxidative NHC catalysis has emerged as a method to convert aldehydes to potent acylating reagents.
Henrik Sundén (1399444)   +15 more
core   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

open access: yesAdvanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu   +8 more
wiley   +1 more source

The function and mechanism of protein acylation in the regulation of viral infection

open access: yesVirulence
Protein acylation modification is one of the most important protein post-translational modifications, which regulates the function of the protein by adding acyl groups to the residues of the protein.
Lei Song   +10 more
doaj   +1 more source

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