Regulation of Dynamic Protein S-Acylation
Frontiers in Molecular Biosciences, 2021 Protein S-acylation is the reversible addition of fatty acids to the cysteine residues of target proteins. It regulates multiple aspects of protein function, including the localization to membranes, intracellular trafficking, protein interactions ...
J. Chen, Ying Fan, D. Boehning
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Cleaner Routes for Friedel-Crafts Acylation [PDF]
, 2010 Friedel-Crafts acylation is among the most fundamental and useful reactions to yield aromatic ketones but it is one of the less acceptable in terms of unwanted polluting by-products or atom economy because of the overconsumption of catalyst which is used
Aribert, Nicolas +4 more
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eLife, 2021 Efficient immune responses require Ca2+ fluxes across ORAI1 channels during engagement of T cell receptors (TCR) at the immune synapse (IS) between T cells and antigen presenting cells. Here, we show that ZDHHC20-mediated S-acylation of the ORAI1 channel
Amado Carreras-Sureda +8 more
semanticscholar +1 more source
Bi-acylation of cellulose: determining the relative reactivities of the acetyl and fatty-acyl moieties [PDF]
, 2011 The global reaction between acetic anhydride and a fatty acid yields, at equilibrium, an asymmetric acetic-aliphatic anhydride in a medium containing finally: acetic-fatty anhydride, acetic anhydride, fatty acid, acetic acid and fatty anhydride.
Borredon, Marie-Elisabeth +2 more
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Lipase catalysed kinetic resolution of racemic 1,2-diols containing a chiral quaternary center [PDF]
, 2018 Optically active 1,2-diols are valuable buildings blocks in organic synthesis. In the present paper, a set of racemic 1,2-diols with an ester functional group are prepared, starting from -ketoesters in a three-step procedure with moderate yields.
Gonzalo Calvo, Gonzalo de
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ATP-independent Control of Vac8 Palmitoylation by a SNARE Subcomplex on Yeast Vacuoles [PDF]
, 2005 Yeast vacuole fusion requires palmitoylated Vac8. We previously showed that Vac8 acylation occurs early in the fusion reaction, is blocked by antibodies against Sec18 (yeast N-ethylmaleimide-sensitive fusion protein (NSF)), and is mediated by the R-SNARE
Cristodero, Marina +5 more
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Pathways of Non-enzymatic Lysine Acylation
Frontiers in Cell and Developmental Biology, 2021 Posttranslational protein modification by lysine acylation is an emerging mechanism of cellular regulation and fine-tunes metabolic processes to environmental changes.
Tim Baldensperger, M. Glomb
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Synthesis of 2-Acylphenol and Flavene Derivatives from the Ruthenium-Catalyzed Oxidative C-H Acylation of Phenols with Aldehydes [PDF]
, 2015 The cationic ruthenium hydride complex [(C6H6)(PCy3)(CO)RuH]+BF4− has been found to be an effective catalyst for the oxidative C–H coupling reaction of phenols with aldehydes to give 2-acylphenol compounds.
Aponick +47 more
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Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution.
Cell Reports, 2021 In addition to acetylation, histones are modified by a series of competing longer-chain acylations. Most of these acylation marks are enriched and co-exist with acetylation on active gene regulatory elements.
Mengqing Gao +23 more
semanticscholar +1 more source
Hybrid bilayer PLA/chitosan nanofibrous scaffolds doped with ZnO, Fe3O4, and Au nanoparticles with bioactive properties for skin tissue engineering [PDF]
, 2020 Burns affect almost half a million of Americans annually. In the case of full-thickness skin injuries, treatment requires a transplant. The development of bioactive materials that promote damaged tissue regeneration constitutes a great alternative to ...
Bogdał, Dariusz +4 more
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