Results 11 to 20 of about 60,893 (292)
Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues [PDF]
, 2008 Glycosylphosphatidylinositol (GPI)-anchored proteins are abundant in the protozoan parasite Trypanosoma brucei, the causative agent of African sleeping sickness in humans and the related disease Nagana in cattle, and disruption of GPI biosynthesis is ...
Nikolaev, Andrei V. +4 more
core +5 more sources
Aldehydes: magnificent acyl equivalents for direct acylation [PDF]
Organic & Biomolecular Chemistry, 2020 This review sheds light on the use of aldehydes in the selective acylation of arene, heteroarene and alkyl (sp 3 , sp 2 and sp) C–H bonds by proficient utilization of the C–H activation strategy.
Kumar, Prashant +7 more
openaire +4 more sources
Cleaner Routes for Friedel-Crafts Acylation [PDF]
, 2010 Friedel-Crafts acylation is among the most fundamental and useful reactions to yield aromatic ketones but it is one of the less acceptable in terms of unwanted polluting by-products or atom economy because of the overconsumption of catalyst which is used
Aribert, Nicolas +4 more
core +1 more source
meta-Selective Radical Acylation of Electron-rich Arenes [PDF]
, 2023 meta-Selective functionalisation of electron-rich arenes provides a non-traditional route to organic synthesis. In classical electrophilic aromatic substitution of electron-donating group-pendant arenes, functionalisation occurs according to ortho- and ...
Masaki , Sano +3 more
core +2 more sources
Site-specific analysis of protein S-acylation by resin-assisted capture[S]
Journal of Lipid Research, 2011 Protein S-acylation is a major posttranslational modification whereby a cysteine thiol is converted to a thioester. A prototype is S-palmitoylation (fatty acylation), in which a protein undergoes acylation with a hydrophobic 16 carbon lipid chain ...
Michael T. Forrester +6 more
doaj +1 more source
Optimization of the Enzymatic Acylation Reaction Conditions of Vitis davidii Malvidin
Shipin gongye ke-ji, 2022 In order to increase the structural stability of anthocyanins, taking Vitis davidii malvidin as sample and the lipase CAL-B as catalyst, the effects of reaction time, temperature, and substrate molar ratio on enzymatic acylation were investigated.
Aili CAI +5 more
doaj +1 more source
Protein Acylation by Saturated Very Long Chain Fatty Acids and Endocytosis Are Involved in Necroptosis [PDF]
, 2020 Necroptosis is a form of regulated cell death that is characterized by membrane permeabilization. This permeabilization is responsible for the inflammatory properties of necroptosis and is critical for disease states involving this process. We previously
Daniel, Lu +12 more
core +1 more source
PLoS ONE, 2021 Mitochondrial trifunctional protein (TFP) is a membrane-associated heterotetramer that catalyzes three of the four reactions needed to chain-shorten long-chain fatty acids inside the mitochondria.
Yuxun Zhang, Eric Goetzman
doaj +1 more source
The Arabidopsis Book, 2010 Acyl lipids in Arabidopsis and all other plants have a myriad of diverse functions. These include providing the core diffusion barrier of the membranes that separates cells and subcellular organelles. This function alone involves more than 10 membrane lipid classes, including the phospholipids, galactolipids, and sphingolipids, and within each class ...
Li-Beisson, Yonghua +26 more
openaire +6 more sources
SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation
eLife, 2017 The Ras family of GTPases are important in cell signaling and frequently mutated in human tumors. Understanding their regulation is thus important for studying biology and human diseases.
Xiaoyu Zhang +4 more
doaj +1 more source