Results 161 to 170 of about 63,314 (347)

SOAT1 Activates NLRP3 Inflammasome to Promote Cancer‐Related Lymphangiogenesis and Metastasis via IL‐1β/IL‐1R‐1 Axis in Oral Squamous Cell Carcinoma

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Oral squamous cell carcinoma (OSCC) is a prevalent type of cancer in the head and neck region, significantly impacting patient survival rates and quality of life. Lymph node (LN) metastasis is a lead contributor to the poor prognosis associated with OSCC.
Chengzhi Zhao   +6 more
wiley   +1 more source

Volatile‐mediated signalling in barley induces metabolic reprogramming and resistance against the biotrophic fungus Blumeria hordei

open access: yesPlant Biology, Volume 25, Issue 1, Page 72-84, January 2023., 2023
After wounding, barley plants emit green leaf volatiles that induce hordatine accumulation and disease resistance in receiver plants. Abstract Plants have evolved diverse secondary metabolites to counteract biotic stress. Volatile organic compounds (VOCs) are released upon herbivore attack or pathogen infection. Recent studies suggest that VOCs can act
S. Laupheimer   +6 more
wiley   +1 more source

Alkyne lipids as substrates for click chemistry-based in vitro enzymatic assays

open access: yesJournal of Lipid Research, 2013
Click chemistry is evolving as a powerful tool in biological applications because it allows the sensitive and specific detection of compounds with alkyne or azido groups.
Anne Gaebler   +5 more
doaj  

Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity

open access: yesJournal of Lipid Research, 2006
Triglyceride synthesis in most mammalian tissues involves the sequential addition of fatty acids to a glycerol backbone, with unique enzymes required to catalyze each acylation step.
Laurent Vergnes   +5 more
doaj  

Immunomodulatory Effects of Omega‐3 Fatty Acids: Mechanistic Insights and Health Implications

open access: yesMolecular Nutrition &Food Research, EarlyView.
Omega‐3 fatty acids, derived from dietary sources and supplements, serve as bioactive precursors (ALA, EPA, DHA) that integrate into immune cell membranes. These fatty acids enhance cell membrane fluidity, improve immune cell communication, and modulate key transcription factors like NF‐κB.
Mahmut Bodur   +3 more
wiley   +1 more source

Acylation of sn-glycerol 3-phosphate by cell fractions of rat liver

open access: yesJournal of Lipid Research, 1968
The esterification of sn-glycerol 3-(dihydrogen phosphate) with long-chain fatty acids by rat liver microsomal preparations has been studied. A newly modified spectrophotometric assay for glycerolphosphate acyltransferase (GP-cyltransferase) compared ...
Harold J. Fallon, Robert G. Lamb
doaj  

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